Evidence map›Paper›PMID 32424676›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022

A machine learning-based approach to directly compare the diagnostic accuracy of myocardial perfusion imaging by conventional and cadmium-zinc telluride SPECT.

Valeria Cantoni, Roberta Green, Carlo Ricciardi, Roberta Assante, Emilia Zampella, Carmela Nappi, Valeria Gaudieri, Teresa Mannarino, Andrea Genova, Giovanni De Simini and 5 more

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  4. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  5. Article
  6. Prone-only SPECT myocardial perfusion imaging: An alternative standard in clinical practice?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Valeria CantoniDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta GreenDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Carlo RicciardiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta AssanteDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Valeria GaudieriDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Teresa MannarinoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Andrea GenovaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Giovanni De SiminiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Alessia GiordanoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Wanda AcampaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Mario PetrettaDepartment of Translational Medical Sciences, University Federico II, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. cuocolo@unina.it.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated the performance of conventional (C) single-photon emission computed tomography (SPECT) and cadmium-zinc-telluride (CZT)-SPECT in a large cohort of patients with suspected or known coronary artery disease (CAD) and compared the diagnostic accuracy of the two systems using machine learning (ML) algorithms. METHODS AND

resultsA total of 517 consecutive patients underwent stress myocardial perfusion imaging (MPI) by both C-SPECT and CZT-SPECT. In the overall population, an excellent correlation between stress MPI data and left ventricular (LV) functional parameters measured by C-SPECT and by CZT-SPECT was observed (all P < .001). ML analysis performed through the implementation of random forest (RF) and k-nearest neighbors (NN) algorithms proved that CZT-SPECT has greater accuracy than C-SPECT in detecting CAD. For both algorithms, the sensitivity of CZT-SPECT (96% for RF and 60% for k-NN) was greater than that of C-SPECT (88% for RF and 53% for k-NN).

conclusionsMPI data and LV functional parameters obtained by CZT-SPECT are highly reproducible and provide good correlation with those obtained by C-SPECT. ML approach showed that the accuracy and sensitivity of CZT-SPECT is greater than C-SPECT in detecting CAD.

Indexed as

Coronary Artery DiseaseMyocardial Perfusion ImagingCadmiumHumansMachine LearningTelluriumTomography, Emission-Computed, Single-PhotonZincCadmiumCdZnTeTelluriumZincCADdiagnostic and prognostic applicationMPISPECT

Identifiers

PMID32424676
OpenAlexW3026434751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.