ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Impact of weight loss on cancer patients' quality of life at the beginning of the chemotherapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Functional Outcomes and Quality of Life for Patients With Cachexia and Solid Tumour Cancers: Findings of a Systematic Literature Review.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- Impact of physical exercise in advanced-stage cancer patients: Systematic review and meta-analysis.Cancer medicine · 2022Pooled it
- Investigating the effects of olanzapine on appetite and weight in patients with cancer in a systematic review.Discover oncology · 2026Review
- Machine learning and the nomogram as the accurate tools for predicting postoperative malnutrition risk in esophageal cancer patients.Frontiers in nutrition · 2025Article
- The relationship between obstructive sleep apnea, dyspnea, and health-related quality of life in lung cancer survivors: a cross-sectional study in the Republic of Korea.Osong public health and research perspectives · 2024Article
- Physical Activity and Epigenetic Aging in Breast Cancer Treatment.International journal of molecular sciences · 2024Article
- The association between malnutrition risk and revised Edmonton Symptom Assessment System (ESAS-r) scores in an adult outpatient oncology population: a cross-sectional study.Journal of patient-reported outcomes · 2024Article
- Obesity Pillars roundtable: Excessive weight reduction with highly effective anti-obesity medications (heAOMs).Obesity pillars · 2022Article
- Comparation of different malnutrition screening tools according to GLIM criteria in cancer outpatients.European journal of clinical nutrition · 2022Observational
- Weight Loss in Advanced Cancer: Sex Differences in Health-Related Quality of Life and Body Image.Life (Basel, Switzerland) · 2022Article
- Nutritional Support in Cancer patients: update of the Italian Intersociety Working Group practical recommendations.Journal of Cancer · 2022Article
- Review
- A Pound of Flesh: What Cachexia Is and What It Is Not.Diagnostics (Basel, Switzerland) · 2021Review
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAmong the prognostic factors relevant to the condition of oncological patients, nutritional status (NS) has the greatest single impact on quality of life (QL). The goals of our study were to evaluate the influence of NS, weight loss (WL), and the presence of cachexia, prior to the initiation of chemotherapy, on the patient's QL.
methodsAdult patients (aged ≥ 18 years) diagnosed with solid tumours for whom chemotherapy was started between April 2016 and June 2017 were eligible for inclusion in the study. They were asked to complete a QL questionnaire (Functional Assessment of Cancer Treatment (FACT-G)) at the beginning. The presence or absence of cachexia was evaluated at the outset, following the definition proposed by Fearon and nutritional assessment by the Patient-Generated Subjective Global Assessment (PG-SGA) scale.
resultsA total of 177 patients completed the FACT-G, the 60% receiving curative therapy. At the start of the treatment, 58.2% of patients had experienced WL, with an average of 4.4 ± 7.4%, and 19% were at risk of malnutrition. Patient who presented cachexia at diagnosis, were treated with palliative intention, had a Nutriscore ≥ 5 points or presented malnutrition in accordance with PG-SGA had a poorer QL (p < 0.05). Greater WL was associated with a worsened QL (p = 0.001). Breast cancer patients presented an inverse correlation between the %WL and the initial score in the FACT-G (r = - 0.304, p = 0.023), whereas no such correlation was observed for the other types of tumour (r = - 0.012, p = 0.892).
conclusionsThese results underline the relation of NS before starting chemotherapy and QL. Greater WL was associated with a worsened QL, especially in women with breast cancer.
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