Trial reportClinical oral investigations2020
Comparison of the effects of injectable platelet-rich fibrin and autologous fibrin glue applications on palatal wound healing: a randomized controlled clinical trial.
Trial report in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Postoperative pain and morbidity at the donor site after palatal soft tissue harvesting: a systematic review.BMC oral health · 2025Pooled it
- Analgesic effects of platelet-rich fibrin (PRF): A systematic review.Periodontology 2000 · 2025Pooled it
- Postoperative pain control after free gingival graft: a systematic review and meta-analysis of RCTS.Brazilian dental journal · 2025Pooled it
- Clinical efficacy of blood derivatives on wound healing: A systematic review and network meta-analysis.International wound journal · 2024Pooled it
- Therapeutic efficacy of platelet-rich fibrin on surgical site wound healing in patients undergoing oral carcinoma resection: A meta-analysis.International wound journal · 2024Pooled it
- Is the use of platelet-rich fibrin effective in the healing, control of pain, and postoperative bleeding in the palatal area after free gingival graft harvesting? A systematic review of randomized clinical studies.Clinical oral investigations · 2021Pooled it
- Is there an effective way to control pain perception after free gingival graft removal? A systematic review and meta-analysis.Brazilian dental journalPooled it
- Comparison of injectable platelet-rich fibrin, titanium platelet-rich fibrin, and 0.8% hyaluronic acid applications versus periodontal dressing alone in wound healing after gingivectomy and gingivoplasty operations: randomized controlled clinical study.Clinical oral investigations · 2026Trial
- The Effect of injectable platelet-rich fibrin and low-level laser therapy on graft shrinkage in free gingival grafts: a randomized controlled clinical trial.BMC oral health · 2026Trial
- Trial
- Cyanoacrylate Adhesive in Free Gingival Graft Healing: A Digital and Microcirculatory Randomized Clinical Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Trial
- Comparative evaluation of hyaluronic acid and injectable platelet-rich fibrin in palatal wound healing: a randomized clinical trial.BMC oral health · 2025Trial
- The efficacy of injectable platelet-rich fibrin versus photobiomodulation therapy on palatal wound healing: a randomized, controlled, clinical trial.Clinical oral investigations · 2025Trial
- Does Injectable Platelet-Rich Fibrin Combined With Autogenous Demineralized Dentine Enhance Alveolar Ridge Preservation? A Randomized Controlled Trial.Clinical oral implants research · 2025Trial
- Efficacy of a Novel Melatonin-Loaded Gelatin Sponge in Palatal Wound Healing.International dental journal · 2024Trial
- Liquid platelet-rich fibrin in root surface biomodification during gingival recession treatment: Randomized, controlled, split-mouth, clinical trial.Clinical and experimental dental research · 2023Trial
- Patient-reported outcomes of palatal donor site healing using four different wound dressing modalities following free epithelialized mucosal grafts: A four-arm randomized controlled clinical trial.Journal of periodontology · 2023Trial
- Sustained insulin-delivery as a growth factor for modulating oral mucosa healing: A case series.Archives of oral biology · 2026Article
- Two-Step Palatal Shield Technique Using Flowable Composite Resin for Donor-Site Protection Following De-Epithelialized Free Gingival Grafting: A Case Report Illustrating a Novel Technique.Case reports in dentistry · 2026Article
- Efficacy of different interventions on the morbidity of the palatal donor area after free gingival graft and connective tissue graft: A systematic review.The Japanese dental science review · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to compare the effects of AFG and i-PRF on palatal wound healing and postoperative discomfort. MATERIALS AND
methodsThirty-six patients in need of FGG were divided into three groups. AFG (n = 12) or i-PRF (n = 12) was applied and compared with control group (n = 12). Wound healing with H
resultsEpithelialization was higher in the test groups on the 14th day than the control group (p < 0.05). MSS scores at the 14th day and 1st month were lower in the AFG group than the control and the i-PRF group (p < 0.05). In the AFG group, LTH levels at the 3rd,7th, and 14th days and 1 month were higher than control and i-PRF groups (p < 0.05). VAS scores of the AFG group were lower than the control and i-PRF groups at the 7th day (p < 0.05). Bleeding was lower in the test groups than in the control group (p < 0.05). There was no difference between the groups in terms of tissue thickness (p > 0.05).
conclusionAFG and i-PRF have positive effects on the healing process by accelerating wound healing and reducing postoperative morbidity. Therewithal, AFG has superior properties in wound healing compared with i-PRF. CLINICAL RELEVANCE: Patient discomfort and pain feeling have a great effect on patient's tendency to surgery and platelet concentrates such as AFG and i-PRF overcome these problems and contribute to patient's quality of life.
Indexed as
Identifiers
32424462What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.