ArticleScientific reports2020
Excitation-inhibition balance and auditory multistable perception are correlated with autistic traits and schizotypy in a non-clinical population.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Sensory processing sensitivity is associated with state-dependent stabilization of perceptual organization in auditory streaming.Communications psychology · 2026Article
- Autistic Traits in Schizophrenia: Immune Mechanisms and Inflammatory Biomarkers.International journal of molecular sciences · 2025Review
- The Relationship Among Range Adaptation, Social Anhedonia, and Social Functioning: A Combined Magnetic Resonance Spectroscopy and Resting-State fMRI Study.Schizophrenia bulletin · 2025Article
- Knowledge mapping of autistic traits: a visual analysis via CiteSpace.Frontiers in psychiatry · 2025Review
- Functional coupling between auditory memory and verbal transformations.Scientific reports · 2024Article
- The Activation of GABAAntioxidants (Basel, Switzerland) · 2024Article
- Association between increased anterior cingulate glutamate and psychotic-like experiences, but not autistic traits in healthy volunteers.Scientific reports · 2023Article
- Visual illusion susceptibility in autism: A neural model.The European journal of neuroscience · 2022Article
- MR-Spectroscopy of GABA and Glutamate/Glutamine Concentrations in Auditory Cortex in Clinical High-Risk for Psychosis Individuals.Frontiers in psychiatry · 2022Article
- The Relationship Between Affective Visual Mismatch Negativity and Interpersonal Difficulties Across Autism and Schizotypal Traits.Frontiers in human neuroscience · 2022Article
- Prediction learning in adults with autism and its molecular correlates.Molecular autism · 2021Article
- Abnormal morphology and subcortical projections to the medial geniculate in an animal model of autism.Experimental brain research · 2021Article
- Lower Ventromedial Prefrontal Cortex Glutamate Levels in Patients With Obsessive-Compulsive Disorder.Frontiers in psychiatry · 2021Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals with autism spectrum disorder and individuals with schizophrenia have impaired social and communication skills. They also have altered auditory perception. This study investigated autistic traits and schizotypy in a non-clinical population as well as the excitation-inhibition (EI) balance in different brain regions and their auditory multistable perception. Thirty-four healthy participants were assessed by the Autism-Spectrum Quotient (AQ) and Schizotypal Personality Questionnaire (SPQ). The EI balance was evaluated by measuring the resting-state concentrations of glutamate-glutamine (Glx) and ϒ-aminobutyric acid (GABA) in vivo by using magnetic resonance spectroscopy. To observe the correlation between their traits and perception, we conducted an auditory streaming task and a verbal transformation task, in which participants reported spontaneous perceptual switching while listening to a sound sequence. Their AQ and SPQ scores were positively correlated with the Glx/GABA ratio in the auditory cortex but not in the frontal areas. These scores were negatively correlated with the number of perceptual switches in the verbal transformation task but not in the auditory streaming task. Our results suggest that the EI balance in the auditory cortex and the perceptual formation of speech are involved in autistic traits and schizotypy.
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