Trial reportTranslational psychiatry2020
Closed-loop digital meditation for neurocognitive and behavioral development in adolescents with childhood neglect.
Trial report in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Adverse childhood experiences and resting state functional connectivity of the triple brain network: a meta-analysis.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- Systematic review of the efficacy of yoga and mindfulness in the management of pediatric obesity.Annals of the New York Academy of Sciences · 2025Pooled it
- The impact of an app-delivered mindfulness-based intervention on resting-state functional connectivity in pediatric concussion: a pilot study.Frontiers in neuroscience · 2026Trial
- Assessing the Impact of a Virtual Reality Cognitive Intervention on Tennis Performance in Junior Tennis Players: Pilot Study.JMIR formative research · 2025Trial
- Closed-Loop Neurofeedback of α Synchrony during Goal-Directed Attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Trial
- Adverse childhood experiences and post-traumatic stress impacts on brain connectivity and alcohol use in adolescence.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025Article
- Breath-Focused Mindfulness and Compassion Training in Parent-Child Dyads: Pilot Intervention Study.JMIR formative research · 2025Article
- Neglect and Neurodevelopment: A Narrative Review Understanding the Link Between Child Neglect and Executive Function Deficits.Biomedicines · 2025Review
- Closed-Loop Systems and Real-Time Neurofeedback in Mindfulness Meditation Research.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Review
- Brief mindfulness coaching enhances selective attention in medical scientists: A pilot study.PloS one · 2025Article
- Personalized Machine Learning-Based Prediction of Wellbeing and Empathy in Healthcare Professionals.Sensors (Basel, Switzerland) · 2024Article
- Design and Implementation of a Brief Digital Mindfulness and Compassion Training App for Health Care Professionals: Cluster Randomized Controlled Trial.JMIR mental health · 2024Article
- Using Digital Measurement-Based Care to Address Symptoms of Inattention, Hyperactivity, and Opposition in Youth: Retrospective Analysis of Bend Health.JMIR formative research · 2023Article
- Enhancing attention in children using an integrated cognitive-physical videogame: A pilot study.NPJ digital medicine · 2023Article
- Leveraging technology to personalize cognitive enhancement methods in aging.Nature aging · 2022Article
- Mindfulness Practice with a Brain-Sensing Device Improved Cognitive Functioning of Elementary School Children: An Exploratory Pilot Study.Brain sciences · 2022Article
- Cognitive and Neural Correlates of Loneliness and Wisdom during Emotional Bias.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Personalized machine learning of depressed mood using wearables.Translational psychiatry · 2021Article
- Reconfiguration of Electroencephalography Microstate Networks after Breath-Focused, Digital Meditation Training.Brain connectivity · 2021Article
- Chronic Mental Health Sequelae of Climate Change Extremes: A Case Study of the Deadliest Californian Wildfire.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse childhood experiences are linked to poor attentive behaviors during adolescence, as well as increased risk for mental health disorders in adults. However, no study has yet tested targeted interventions to optimize neurocognitive processes in this population. Here, we investigated closed-loop digital interventions in a double-blind randomized controlled study in adolescents with childhood neglect, and evaluated the outcomes using multimodal assessments of neuroimaging, cognitive, behavioral, and academic evaluations. In the primary neuroimaging results, we demonstrate that a closed-loop digital meditation intervention can strengthen functional connectivity of the dorsal anterior cingulate cortex (dACC) in the cingulo-opercular network, which is critically developing during the adolescent period. Second, this intervention enhanced sustained attention and interference-resolution abilities, and also reduced behavioral hyperactivity at a 1-year follow-up. Superior academic performance was additionally observed in adolescents who underwent the digital meditation intervention. Finally, changes in dACC functional connectivity significantly correlated with improvements in sustained attention, hyperactivity, and academic performance. This first study demonstrates that closed-loop digital meditation practice can facilitate development of important aspects of neurocognition and real-life behaviors in adolescents with early childhood neglect.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.