ArticleScientific reports2020
Impact of implementing a non-restrictive antibiotic stewardship program in an emergency department: a four-year quasi-experimental prospective study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Impact of a persuasive antimicrobial stewardship program on antibiotic use in patients admitted to emergency department for urinary tract infections: a multicentre prospective study.Antimicrobial resistance and infection control · 2025Article
- Sepsis in the emergency department: a dual challenge of early management and antimicrobial stewardship.BMC infectious diseases · 2025Article
- Article
- Antimicrobial Stewardship in the Emergency Department Observation Unit: Definition of a New Indicator and Evaluation of Antimicrobial Use and Clinical Outcomes.Antibiotics (Basel, Switzerland) · 2024Article
- The impact of a non-restrictive Antimicrobial Stewardship Program in the emergency department of a secondary-level Italian hospital.Internal and emergency medicine · 2024Article
- Prioritizing Equity in Antimicrobial Stewardship Efforts (EASE): a framework for infectious diseases clinicians.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Review
- Antimicrobial resistance control in the emergency department: a need for concrete improvement.Antimicrobial resistance and infection control · 2022Article
- The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience.Innovations in pharmacy · 2022Article
- Paediatric Antimicrobial Stewardship for Respiratory Infections in the Emergency Setting: A Systematic Review.Antibiotics (Basel, Switzerland) · 2021Review
- Guidelines on Implementing Antimicrobial Stewardship Programs in Korea.Infection & chemotherapy · 2021Review
- Antimicrobial Stewardship: Fighting Antimicrobial Resistance and Protecting Global Public Health.Infection and drug resistance · 2020Review
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic resistance is increasing worldwide. The implementation of antibiotic stewardship programmes (ASPs) is of utmost importance to optimize antibiotic use in order to prevent resistance development without harming patients. The emergency department (ED), cornerstone between hospital and community, represents a crucial setting for addressing ASP implementation; however, evidence data on ASP in ED are poor. In this study, a 4-year, non-restrictive, multi-faceted ASP was implemented in a general ED with the aim to evaluate its impact on antibiotic use and costs. Secondly, the study focused on assessing the impact on length of hospital stay (LOS), Clostridioides difficile infection (CDI) incidence rate, and mortality in the patients' group admitted from ED to medical wards. The ASP implementation was associated with a reduction of antibiotic use and costs. A mild but sustained LOS decrease in all medical wards and a significant downward trend of CDI incidence rate were observed, while mortality did not significantly change. In conclusion, the implementation of our ED-based ASP has demonstrated to be feasible and safe and might clinically benefit the hospital admitted patients' group. Further research is needed to identify the most suitable ASP design for ED and the key outcome measures to reliably assess its effectiveness.
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