ArticleNature communications2020
Manipulating the fluorescence lifetime at the sub-cellular scale via photo-switchable barcoding.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Encoded Microspheres in Multiplex Detection of Mycotoxins and Other Analytes.Foods (Basel, Switzerland) · 2026Review
- A distinct neural ensemble to integrate contradictory information and form long-term memory inScience advances · 2025Article
- Design Principles of Nanosensors for Multiplex Detection of Contaminants in Food.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Complex-mediated nucleophilic aromatic substitution with aryl nitriles to realize intramolecular flapping-restricted D-A AIEgens for bioimaging.Smart molecules : open access · 2025Article
- Self-Reporting Therapeutic Protein Nanoparticles.ACS applied materials & interfaces · 2024Article
- Photoswitching the fluorescence of nanoparticles for advanced optical applications.Chemical science · 2024Review
- Amplifying dual-visible-light photoswitching in aqueous mediaChemical science · 2024Article
- Control of the fluorescence lifetime in dye based nanoparticles.Chemical science · 2024Article
- Structural Determinants of Stimuli-Responsiveness in Amphiphilic Macromolecular Nano-assemblies.Progress in polymer science · 2024Article
- Ligand-protected nanocluster-mediated photoswitchable fluorescent nanoprobes towards dual-color cellular imaging.Chemical science · 2023Article
- Identification of fluorescently-barcoded nanoparticles using machine learning.Nanoscale advances · 2023Article
- Narrowband photoblinking InP/ZnSe/ZnS quantum dots for super-resolution multifocal structured illumination microscopy enhanced by optical fluctuation.Nanophotonics (Berlin, Germany) · 2023Article
- Water-Stable Carborane-Based EuChemistry of materials : a publication of the American Chemical Society · 2022Article
- Review
- Lysosome purinergic receptor P2X4 regulates neoangiogenesis induced by microvesicles from sarcoma patients.Cell death & disease · 2021Article
- Rigidochromism by imide functionalisation of an aminomaleimide fluorophore.Chemical science · 2021Article
- A fluorescent calix[4]arene with naphthalene units at the upper rim exhibits long fluorescence emission lifetime without fluorescence quenching.RSC advances · 2021Article
- Multiplexed optical barcoding of cellsChemical science · 2021Article
- Near-Infrared Inorganic Nanomaterials for Precise Diagnosis and Therapy.Frontiers in bioengineering and biotechnology · 2021Review
- Activatable fluorescence sensors forChemical science · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluorescent barcoding is a pivotal technique for the investigation of the microscale world, from information storage to the monitoring of dynamic biochemical processes. Using fluorescence lifetime as the readout modality offers more reproducible and quantitative outputs compared to conventional fluorescent barcoding, being independent of sample concentration and measurement methods. However, the use of fluorescence lifetime in this area has been limited by the lack of strategies that provide spatiotemporal manipulation of the coding process. In this study, we design a two-component photo-switchable nanogel that exhibits variable fluorescence lifetime upon photoisomerization-induced energy transfer processes through light irradiation. This remotely manipulated fluorescence lifetime property could be visually mapped using fluorescence lifetime imaging microscopy (FLIM), allowing selective storage and display of information at the microscale. Most importantly, the reversibility of this system further provides a strategy for minimizing the background influence in fluorescence lifetime imaging of live cells and sub-cellular organelles.
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Registered trials
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