ArticleScientific reports2020
New chlamydosporol derivatives from the endophytic fungus Pleosporales sp. Sigrf05 and their cytotoxic and antimicrobial activities.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Production of bioactive spirodioxynaphthalenes from Hermatomyces reticulatus (Pleosporales).Folia microbiologica · 2026Article
- Metabolomics-Guided Discovery of Bipolarolides H-O, New Ophiobolin-Type Sesterterpenes with Antibacterial Activity from the Marine-Derived FungusJournal of natural products · 2025Article
- Endophytic Fungi: A Treasure Trove of Antifungal Metabolites.Microorganisms · 2024Review
- ( ±)-Dibrevianamides Q1 and Q2, the key precursors of asperginulin A from a marine-derived fungus.Applied microbiology and biotechnology · 2023Article
- Natural Bacterial and Fungal Peptides as a Promising Treatment to Defeat Lung Cancer Cells.Molecules (Basel, Switzerland) · 2023Review
- Improvement in the Phytochemical Content and Biological Properties ofPlants (Basel, Switzerland) · 2023Article
- Systematically Investigating the Pharmacological Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2023Article
- Fungal Endophytes: A Potential Source of Antibacterial Compounds.Journal of fungi (Basel, Switzerland) · 2022Review
- Metabolites of medicine food homology-derived endophytic fungi and their activities.Current research in food science · 2022Review
- Endophytic fungi: A treasure trove of novel anticancer compounds.Current research in pharmacology and drug discovery · 2021Article
- Eremophilane-Type Sesquiterpenoids From the Endophytic FungusFrontiers in chemistry · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Five new chlamydosporol derivatives, named pleospyrones A-E (1-5), together with one known congener (6), were isolated from the culture of the endophytic fungus Pleosporales sp. Sigrf05, obtained from the medicinal plant Siraitia grosvenorii. The structures of the new compounds were elucidated mainly by analysis of the HRESIMS, and (1D, 2D) NMR data, while ECD and optical rotation calculations were used to assign the absolute configurations. The plausible biosynthetic pathway of these compounds were proposed. The isolated compounds were evaluated for their cytotoxicity, antifungal and antibacterial activities. Compounds 1, and 4-6 were cytotoxic against the tested cancer cells with IC
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