ArticleeNeuro
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Diffusion Tensor Imaging-Based Studies at the Group-Level Applied to Animal Models of Neurodegenerative Diseases.Frontiers in neuroscience · 2020Pooled it
- Autoencoders for unsupervised analysis of rat myeloarchitecture.Brain structure & function · 2026Article
- Data-driven classification of tissue water populations by massively multidimensional diffusion-relaxation correlation MRI.Frontiers in neuroscience · 2026Article
- Scattering approach to diffusion quantifies axonal damage in brain injury.Nature communications · 2025Article
- White Matter Integrity in Women with Repetitive Traumatic Brain Injury due to Intimate Partner Violence.Journal of neurotrauma · 2025Article
- Article
- Evidence Suggesting Prolonged Neuroinflammation in a Subset of Children after Moderate/Severe TBI: A UCLA RAPBI Study.medRxiv : the preprint server for health sciences · 2025Article
- Evaluating the therapeutic effect of LIPUS in the early stage of traumatic brain injury using FA and T2Aging · 2024Article
- Anisotropy component of DTI reveals long-term neuroinflammation following repetitive mild traumatic brain injury in rats.European radiology experimental · 2024Article
- Modified constraint-induced movement therapy enhances cortical plasticity in a rat model of traumatic brain injury: a resting-state functional MRI study.Neural regeneration research · 2023Article
- Initial Severity of Injury Has Little Effect on the Temporal Profile of Long-Term Deficits in Locomotion, Anxiety, and Cognitive Function After Diffuse Traumatic Brain Injury.Neurotrauma reports · 2023Article
- A multiscale tissue assessment in a rat model of mild traumatic brain injury.Journal of neuropathology and experimental neurology · 2022Article
- Stem Cell Therapy for Sequestration of Traumatic Brain Injury-Induced Inflammation.International journal of molecular sciences · 2022Review
- Financial decision-making and self-awareness for financial decision-making is associated with white matter integrity in older adults.Human brain mapping · 2022Article
- Histopathological modeling of status epilepticus-induced brain damage based onFrontiers in neuroscience · 2022Article
- From biomechanics to pathology: predicting axonal injury from patterns of strain after traumatic brain injury.Brain : a journal of neurology · 2021Article
- Microstructural Tissue Changes in a Rat Model of Mild Traumatic Brain Injury.Frontiers in neuroscience · 2021Article
- Advances in Brain Imaging Techniques for Patients With Intractable Epilepsy.Frontiers in neuroscience · 2021Review
- Structural Myelin Mapping in Individuals with a History of Head Injury.Neurotrauma reportsArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mild traumatic brain injury (mTBI) is the most common form of TBI with 10-25% of the patients experiencing long-lasting symptoms. The potential of diffusion tensor imaging (DTI) for evaluating microstructural damage after TBI is widely recognized, but the interpretation of DTI changes and their relationship with the underlying tissue damage is unclear. We studied how both axonal damage and gliosis contribute to DTI alterations after mTBI. We induced mTBI using the lateral fluid percussion (LFP) injury model in adult male Sprague Dawley rats and scanned them at 3 and 28 d post-mTBI. To characterize the DTI findings in the tissue, we assessed the histology by performing structure tensor (ST)-based analysis and cell counting on myelin-stained and Nissl-stained sections, respectively. In particular, we studied the contribution of two tissue components, myelinated axons and cellularity, to the DTI changes. Fractional anisotropy (FA), mean diffusivity (MD), and axial diffusivity (AD) were decreased in both white and gray matter areas in the acute phase post-mTBI, mainly at the primary lesion site. In the subacute phase, FA and AD were decreased in the white matter, external capsule, corpus callosum, and internal capsule. Our quantitative histologic assessment revealed axonal damage and gliosis throughout the brain in both white and gray matter, consistent with the FA and AD changes. Our findings suggest that the usefulness of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.