Evidence map›Paper›PMID 32424001›Full record

ArticleJournal of the American Society of Nephrology : JASN2020

Inhibition of Estrogen Sulfotransferase (

Anne C Silva Barbosa, Dong Zhou, Yang Xie, You-Jin Choi, Hung-Chun Tung, Xinyun Chen, Meishu Xu, Robert B Gibbs, Samuel M Poloyac, Silvia Liu and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Anne C Silva BarbosaCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Dong ZhouDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yang XieCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania wex6@pitt.edu.ORCID 0000-0002-2190-6966
You-Jin ChoiCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Hung-Chun TungCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Xinyun ChenCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Meishu XuCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Robert B GibbsDepartment of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Samuel M PoloyacDepartment of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-6716-913X
Silvia LiuDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yanping YuDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jianhua LuoDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Youhua LiuDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-4740-805X
Wen XieCenter for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania wex6@pitt.edu.
University of Pittsburgh · US

Funding

Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Satdarshan Singh Monga · 2019 to 2026
$10.9M
Xenobiotic Receptors in Mediating the Environmental Effects on Human Disease and MorbidityR35ES030429 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Wen Xie · 2019 to 2026
$6.9M
PXR-Mediated Xenobiotic Response in the Pathogenesis Hemorrhagic ShockR01DK117370 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI XIE, WEN · 2019 to 2022
$1.4M
Early and Transient Activation of Fibroblasts Promotes Tubule Repair after Acute Kidney InjuryK01DK116816 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHOU, DONG · 2019 to 2021
$509k
API 4000 QTRAPS10RR023461 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI POLOYAC, SAMUEL M · 2007 to 2007
$487k
NCRR NIH HHS S10 RR023461NIDDK NIH HHS K01 DK116816NIDDK NIH HHS P30 DK120531NIDDK NIH HHS R01 DK117370NIEHS NIH HHS R35 ES030429
6 · The paper itself

Abstract

backgroundStudies have suggested that estrogens may protect mice from AKI. Estrogen sulfotransferase (

methodsWe used the renal ischemia-reperfusion model to investigate the role of

resultsAKI induced the expression of

conclusions

Indexed as

Acute Kidney InjuryAnimalsCalcitriolDisease Models, AnimalEnzyme InhibitorsFemaleGene ExpressionGene Expression ProfilingInflammationInterleukin-1betaInterleukin-6KidneyLiverMaleMiceMice, KnockoutCalcitriolEnzyme Inhibitorsestrone sulfotransferaseIL1B protein, mouseInterleukin-1betaInterleukin-6interleukin-6, mouseReceptors, CalcitriolSulfotransferasesTriclosanacute kidney injurycalcitriolestrogen sulfotransferasekidney-liver crosstalkrenal ischemia-reperfusion

Identifiers

PMID32424001
PMCPMC7351010
OpenAlexW3027661062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.