Evidence map›Paper›PMID 32423992›Full record

ArticleMolecular and cellular biology2020

Isc10, an Inhibitor That Links the Anaphase-Promoting Complex to a Meiosis-Specific Mitogen-Activated Protein Kinase.

Abhimannyu Rimal, Zeal P Kamdar, Chong Wai Tio, Edward Winter

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Membrane and organelle rearrangement during ascospore formation in budding yeast.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  3. Article
  4. Meiotic Cytokinesis inJournal of fungi (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Abhimannyu RimalDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Zeal P KamdarDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Chong Wai TioDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Edward WinterDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA edward.winter@jefferson.edu.
Thomas Jefferson University · US

Funding

Non-canonical MAPK signaling in yeastR01GM120090 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI WINTER, EDWARD P · 2016 to 2023
$2.6M
NIGMS NIH HHS R01 GM120090
6 · The paper itself

Abstract

Smk1 is a meiosis-specific mitogen-activated protein kinase (MAPK) in yeast that controls spore differentiation. It is activated by a MAPK binding protein, Ssp2, upon completion of the meiotic divisions. The activation of Smk1 by Ssp2 is positively regulated by a meiosis-specific coactivator of the anaphase promoting complex (APC/C) E3 ubiquitin ligase, Ama1. Here, we identify Isc10 as an inhibitor that links APC/C

Indexed as

AnaphaseAnaphase-Promoting Complex-CyclosomeCdc20 ProteinsCell Cycle ProteinsGene Expression Regulation, FungalMitogen-Activated Protein KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSpores, FungalAnaphase-Promoting Complex-CyclosomeCdc20 ProteinsCell Cycle ProteinsISC10 protein, S cerevisiaeMitogen-Activated Protein KinasesSaccharomyces cerevisiae ProteinsAma1anaphase promoting complexmeiosismitogen-activated protein kinasesSmk1yeasts

Identifiers

PMID32423992
PMCPMC7394827
OpenAlexW3027160087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.