Evidence map›Paper›PMID 32423991›Full record

ArticleMolecular and cellular biology2020

Circular RNA CDR1as Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.

Dingyang Li, Zhe Tang, Zhiqiang Gao, Pengcheng Shen, Zhaochen Liu, Xiaowei Dang

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. The diverse roles of circular RNAs in cholangiocarcinoma.Medical oncology (Northwood, London, England) · 2025
    Review
  6. Review
  7. Review
  8. Long Non-Coding RNA LINC01123 Facilitates Cholangiocarcinoma Aggravation by Targeting miR-641.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Circ_0001946 Promotes the Development of Acute Myeloid Leukemia by Upregulating PDL1Turkish journal of haematology : official journal of Turkish Society of Haematology · 2023
    Article
  14. Article
  15. Potential mechanism of circRNA_000585 in cholangiocarcinoma.The Journal of international medical research · 2021
    Article
  16. Review
  17. Article
  18. Article
  19. CircRNA ciRS-7: a Novel Oncogene in Multiple Cancers.International journal of biological sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dingyang LiDepartment of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Zhe TangDepartment of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Zhiqiang GaoDepartment of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Pengcheng ShenDepartment of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Zhaochen LiuDepartment of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Xiaowei DangDepartment of Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China dxw1428@sina.com.ORCID 0000-0002-8661-3507
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been found that the circular RNA (circRNA) CDR1as is upregulated in cholangiocarcinoma (CCA) tissues. In this study, we tried to explore the roles of CDR1as in CCA. CDR1as was overexpressed or knocked down in human CCA cells to assess the effects of CDR1as on cell behaviors and tumor xenograft growth.

Indexed as

AutoantigensBile Duct NeoplasmsBile Ducts, IntrahepaticCarcinogenesisCell Line, TumorCell ProliferationCholangiocarcinomaGene Expression Regulation, NeoplasticHumansMicroRNAsNerve Tissue ProteinsRNA, CircularRNA, Long NoncodingAutoantigensCDR1 protein, humanMicroRNAsMIRN641 microRNA, humanNerve Tissue ProteinsRNA, CircularRNA, Long NoncodingAKT3/mTOR pathwaycholangiocarcinomacircular CDR1asmiR-641

Identifiers

PMID32423991
PMCPMC7364046
OpenAlexW3025266589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.