Evidence map›Paper›PMID 32423961›Full record

ArticleAntimicrobial agents and chemotherapy2020

Chemokine CCL28 Is a Potent Therapeutic Agent for Oropharyngeal Candidiasis.

Jie He, Monica A Thomas, Jaime de Anda, Michelle W Lee, Emma Van Why, Pippa Simpson, Gerard C L Wong, Mitchell H Grayson, Brian F Volkman, Anna R Huppler

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  5. Review
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  8. Review
  9. Metamorphic Protein Folding Encodes Multiple Anti-Pathogens (Basel, Switzerland) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jie HeDepartment of Pediatrics, Division of Infectious Disease, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Monica A ThomasDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Jaime de AndaDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California, USA.
Michelle W LeeDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California, USA.
Emma Van WhyDepartment of Pediatrics, Division of Infectious Disease, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Pippa SimpsonDepartment of Pediatrics, Division of Quantitative Health Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Gerard C L WongDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, California, USA.
Mitchell H GraysonDepartment of Pediatrics, Division of Allergy and Immunology, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Brian F VolkmanDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Anna R HupplerDepartment of Pediatrics, Division of Infectious Disease, Medical College of Wisconsin, Milwaukee, Wisconsin, USA ahuppler@mcw.edu.
Medical College of Wisconsin · USUniversity of California, Los Angeles · USThe Ohio State University · US

Funding

Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
Cathelicidins in Skin ImmunityR01AI052453 · NIAID · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L, NIZET, VICTOR · 2002 to 2017
$5.3M
Targeting CCL28 as therapy for obstructive lung diseaseR01AI120655 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI VOLKMAN, BRIAN F · 2015 to 2018
$1.5M
Anti-Candida activity of CCL28 in oropharyngeal candidiasisK08DE026189 · NIDCR · MEDICAL COLLEGE OF WISCONSIN · PI HUPPLER, ANNA · 2017 to 2021
$860k
Validating CCL28 as a Target for Novel Asthma Therapies using NMR SpectroscopyF30HL134253 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI THOMAS, MONICA A · 2017 to 2019
$140k
NHLBI NIH HHS F30 HL134253NIAID NIH HHS R01 AI052453NIAID NIH HHS R01 AI120655NIDCR NIH HHS K08 DE026189NIDCR NIH HHS L40 DE027274NIGMS NIH HHS T32 GM080202
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsCandidiasis, OralAnimalsCandida albicansChemokinesChemokines, CCMiceMicrobial Sensitivity TestsAntifungal AgentsCcl28 protein, mouseChemokinesChemokines, CCantifungalantimicrobial peptideCandidachemokineoropharyngeal candidiasis

Identifiers

PMID32423961
PMCPMC7526824
OpenAlexW3027571557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.