Evidence map›Paper›PMID 32423925›Full record

SynthesisBMJ open2020

Behavioural and pharmaceutical interventions for the prevention of skin cancers in solid organ transplant recipients: a systematic review of randomised controlled trials.

Laura J James, Valeria Saglimbene, Germaine Wong, Allison Tong, Laurence Don Wai Luu, Jonathan Craig, Kirsten Howard, Martin Howell

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Laura J JamesSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia laura.james@health.nsw.gov.au.ORCID 0000-0002-0635-8420
Valeria SaglimbeneSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Germaine WongSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Allison TongSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Laurence Don Wai LuuSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Jonathan CraigCollege of Medicine and Public Health, Flinders University Faculty of Medicine Nursing and Health Sciences, Adelaide, South Australia, Australia.
Kirsten HowardSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Martin HowellSydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-9740-712X
The University of Sydney · AUFlinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSolid organ transplant recipients are at increased risk of skin cancer, affecting more than 50% of recipients. We aimed to determine the effectiveness of interventions for behavioural change for sun protection or skin cancer prevention in solid organ transplant recipients.

designSystematic review. DATA SOURCES: We searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL) and CINAHL from inception to November 2019. ELIGIBILITY CRITERIA: We included randomised controlled trials that evaluated the effect of behavioural or pharmaceutical interventions on behavioural change or skin cancer prevention in solid organ transplant recipients. DATA EXTRACTION AND SYNTHESIS: Risks of bias and evidence certainty were assessed using Cochrane and the Grading of Recommendations Assessment Development and Evaluation framework.

resultsTwenty trials (n=2295 participants) were included. It is uncertain whether behavioural interventions improve sun protection behaviour (n=3, n=414, standardised mean difference (SMD) 0.89, 95% CI -0.84 to 2.62, I

conclusionsBehavioural and pharmaceutical preventive interventions may improve sun protective behaviour and knowledge, and reduce the incidence of non-melanocytic skin cancer, but the overall quality of the evidence is very low and insufficient to guide decision-making and clinical practice. PROSPERO REGISTRATION NUMBER: CRD42017063962.

Indexed as

Pharmaceutical PreparationsRandomized Controlled Trials as TopicSkin NeoplasmsFemaleHumansMalePharmaceutical Preparationsmelanomapreventionskin cancersun protectionsun protection behaviours

Identifiers

PMID32423925
PMCPMC7239542
OpenAlexW3025927364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.