ArticleJournal of cardiothoracic and vascular anesthesia2021
Is the Obesity Paradox in Cardiac Surgery Really a Myth? Effect of Body Mass Index on Early and Late Clinical Outcomes.
Article in Journal of cardiothoracic and vascular anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Mortality risk in patients with underweight or obesity with peripheral artery disease: a meta-analysis including 5,735,578 individuals.International journal of obesity (2005) · 2022Pooled it
- Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study.Frontiers in cardiovascular medicine · 2022Pooled it
- Gender-specific differences in body mass index and cardiovascular risk adversely impact survival after aortic valve replacement.Cardiovascular diagnosis and therapy · 2025Article
- Minimally invasive aortic valve replacement in morbidly obese patients: outcomes from a cohort study and pooled data analysis.Frontiers in cardiovascular medicine · 2025Article
- Artificial intelligence-based analysis of body composition predicts outcome in patients receiving long-term mechanical circulatory support.Journal of cachexia, sarcopenia and muscle · 2024Article
- The Burden of Obesity in Cardiac Surgery: A 14 years' Follow-Up of 14.754 Patients.Journal of obesity · 2024Article
- Effect of body mass index on clinical outcomes after robotic cardiac surgery: is there an obesity paradox?BMC cardiovascular disorders · 2023Article
- Clearing Up the Obesity Paradox in Cardiac Surgery.Journal of cardiothoracic and vascular anesthesia · 2021Article
- Overweight is associated with better one-year survival in elderly patients after cardiac surgery: a retrospective analysis of the MIMIC-III database.Journal of thoracic disease · 2021Article
- Combined Effect of Famine Exposure and Obesity Parameters on Hypertension in the Midaged and Older Adult: A Population-Based Cross-Sectional Study.BioMed research international · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe present study was conducted to investigate the obesity paradox and assess the effect of body mass index (BMI) on early and late clinical outcomes after cardiac surgery.
designCohort study with a retrospective analysis of prospectively collected data.
designSingle-institution cardiology medical center.
participantsThe study comprised consecutive patients undergoing cardiac surgery from January 2009 to January 2019. Patients were divided into the following 4 groups defined by BMI: underweight (UW) (≤18.5 kg/m
interventionsNo interventions. MEASUREMENTS AND MAIN
resultsA multivariate analysis was used to compare clinical outcomes among the different BMI groups. Overall 1-year survival of patients in the BMI categories was determined by the Kaplan-Meier method and compared using the log rank test. The study included 5,419 patients. The BMI groups were significantly different regarding presurgical variables. Mortality according to BMI exhibited a reverse J-shaped relationship: 7.4% in the UW group, 5.2% in the normal weight group, 3.2% in the OW group, and 4.3% in the OB group (p = 0.016). Low- cardiac- output syndrome and bleeding were more frequent in the UW group, whereas mediastinitis and hyperglycemia were more common in the OB group. After adjusting for other risk factors, BMI was not an independent predictor of in-hospital mortality. One-year follow-up was completed in 95% of the patients, and the analysis of long-term mortality did not show a difference among the BMI categories (p log rank = 0.16).
conclusionOW patients had a lower mortality and better outcomes after cardiac surgery. However, when other preoperative variables were taken into account, BMI did not have independent effect on in-hospital and 1-year mortality.
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