Evidence map›Paper›PMID 32423667›Full record

ArticleEnzyme and microbial technology2020

Semi-rational approach to expand the Acyl-CoA Chain length tolerance of Sphingomonas paucimobilis serine palmitoyltransferase.

Hyunjun Choe, Minsun Cha, Jon D Stewart

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Enzyme and microbial technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hyunjun ChoeDepartment of Chemistry, 126 Sisler Hall, University of Florida, Gainesville, FL 32611 USA.
Minsun ChaDepartment of Chemistry, 126 Sisler Hall, University of Florida, Gainesville, FL 32611 USA.
Jon D StewartDepartment of Chemistry, 126 Sisler Hall, University of Florida, Gainesville, FL 32611 USA. Electronic address: jds2@chem.ufl.edu.
University of Florida · US

Funding

Acquisition of a Q Exactive HF Hybrid Quadrupole-OrbitrapS10OD021758 · OD · UNIVERSITY OF FLORIDA · PI BASSO, KARI B · 2017 to 2017
$600k
NIH HHS S10 OD021758
6 · The paper itself

Abstract

Serine palmitoyltransferase (SPTase), the first enzyme of the sphingolipid biosynthesis pathway, produces 3-ketodihydrosphingosine by a Claisen-like condensation/decarboxylation reaction of l-Ser and palmitoyl-CoA (n-C

Indexed as

Acyl Coenzyme ABacterial ProteinsCatalytic DomainHigh-Throughput Screening AssaysMetabolic EngineeringModels, MolecularSerine C-PalmitoyltransferaseSphingomonasSphingosineSubstrate SpecificityAcyl Coenzyme ABacterial ProteinsketodihydrosphingosineSerine C-PalmitoyltransferaseSphingosineC-C bond-forming reactionEnzyme engineeringEnzyme library screeningSerine palmitoyltransferaseSphingolipidsSubstrate tolerance

Identifiers

PMID32423667
PMCPMC7239952
OpenAlexW3001659990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.