Evidence map›Paper›PMID 32423501›Full record

ArticleBJPsych open2020

Impact of dissociation on the effectiveness of psychotherapy for post-traumatic stress disorder: meta-analysis.

C M Hoeboer, R A De Kleine, M L Molendijk, M Schoorl, D A C Oprel, J Mouthaan, W Van der Does, A Van Minnen

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

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  19. Dissociation, trauma, and borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

C M HoeboerLeiden University, Institute of Psychology; and Parnassiagroep, PsyQ, The Hague, the Netherlands.ORCID https://orcid.org/0000-0002-5991-1963
R A De KleineLeiden University, Institute of Psychology, the Netherlands.
M L MolendijkLeiden University, Institute of Psychology, the Netherlands.ORCID https://orcid.org/0000-0002-2204-9361
M SchoorlLeiden University, Institute of Psychology; and Parnassiagroep, PsyQ, The Hague, the Netherlands.
D A C OprelLeiden University, Institute of Psychology; and Parnassiagroep, PsyQ, The Hague, the Netherlands.
J MouthaanLeiden University, Institute of Psychology, the Netherlands.
W Van der DoesLeiden University, Institute of Psychology; Parnassiagroep, PsyQ The Hague, the Netherlands; and Department of Psychiatry, Leiden University Medical Center, the Netherlands.
A Van MinnenPSYTREC, Bilthoven; and Radboud University, Behavioural Science Institute, the Netherlands.
Leiden University · NLParnassia Groep · NLLeiden University Medical Center · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany patients with post-traumatic stress disorder (PTSD) experience dissociative symptoms. The question of whether these dissociative symptoms negatively influence the effectiveness of psychotherapy for PTSD is unresolved.

aimsTo determine the influence of dissociative symptoms on psychotherapy outcome in PTSD.

methodWe conducted a systematic search in Cochrane, Embase, PILOTS, PsycINFO, PubMed and Web of Science for relevant clinical trials. A random-effects meta-analysis examined the impact of dissociation on psychotherapy outcome in PTSD (pre-registered at Prospero CRD42018086575).

resultsTwenty-one trials (of which nine were randomised controlled trials) with 1714 patients were included. Pre-treatment dissociation was not related to treatment effectiveness in patients with PTSD (Pearson's correlation coefficient 0.04, 95% CI -0.04 to 0.13). Between-study heterogeneity was high but was not explained by moderators such as trauma focus of the psychotherapy or risk of bias score. There was no indication for publication bias.

conclusionsWe found no evidence that dissociation moderates the effectiveness of psychotherapy for PTSD. The quality of some of the included studies was relatively low, emphasising the need for high-quality clinical trials in patients with PTSD. The results suggest that pre-treatment dissociation does not determine psychotherapy outcome in PTSD.

Indexed as

Dissociative disordersgroup psychotherapyindividual psychotherapypost-traumatic stress disorder

Identifiers

PMID32423501
PMCPMC7345665
OpenAlexW3027838418

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.