Evidence map›Paper›PMID 32423456›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2020

A comparison of cine CMR imaging at 0.55 T and 1.5 T.

W Patricia Bandettini, Sujata M Shanbhag, Christine Mancini, Delaney R McGuirt, Peter Kellman, Hui Xue, Jennifer L Henry, Margaret Lowery, Swee Lay Thein, Marcus Y Chen and 1 more

2 registry-linked trialsOpen access · goldAbstract readComparative StudyValidation Study
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03331380 narecruitingnot on this map

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2018 to 2028Enrolled2,950ConditionsCADArmsMRI scan - obj 1, MRI scans - obj 2, MRI scans - obj 3, MRI scans - obj 4
NCT03581318 recruitingnot on this map

Technical and Translational Development of Cardiovascular MRI (CMR)

TypeobservationalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2018 to 2028Enrolled5,000ConditionsNormal and Abnormal Cardiovascular Physiology
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Society for Cardiovascular Magnetic Resonance recommendations toward environmentally sustainable cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Measuring biventricular function and left atrial volume in a single five-dimensional whole-heart cardiovascular magnetic resonance scan at 0.55T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Cardiac MRI at Low Field Strengths.Journal of magnetic resonance imaging : JMRI · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Low-field MRI: A report on the 2022 ISMRM workshop.Magnetic resonance in medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

W Patricia BandettiniCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Sujata M ShanbhagCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Christine ManciniCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Delaney R McGuirtCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Peter KellmanCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Hui XueCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Jennifer L HenryCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Margaret LoweryCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Swee Lay TheinSickle Cell Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.
Marcus Y ChenCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA.
Adrienne E Campbell-WashburnCardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Department of Health and Human Services, Building 10, Room BID-47, 10 Center Dr, Bethesda, MD, 20892, USA. adrienne.campbell@nih.gov.
National Heart Lung and Blood Institute · USNational Institutes of Health · US

Funding

Cardiovascular CT Clinical ResearchZIAHL006220 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHEN, MARCUS · 2017 to 2025
$22.5M
Gadgetron Global Network and Intelligence Computing: Clinical Imaging Application Development and Software InfrastructureZIAHL006214 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KELLMAN, PETER · 2016 to 2025
$7.3M
Innovative Technology for MRI Guided ProceduresZIAHL006213 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2016 to 2025
$5.4M
Intramural NIH HHS ZIA HL006213Intramural NIH HHS ZIA HL006220
6 · The paper itself

Abstract

backgroundThere is a renewed interest in lower field magnetic resonance imaging (MRI) systems for cardiovascular magnetic resonance (CMR), due to their favorable physical properties, reduced costs, and increased accessibility to patients with implants. We sought to assess the diagnostic capabilities of high-performance low-field (0.55 T) CMR imaging for quantification of right and left ventricular volumes and systolic function in both healthy subjects and patients referred for clinical CMR.

methodsSixty-five subjects underwent paired exams at 1.5 T using a clinical CMR scanner and using an identical CMR system modified to operate at 0.55 T. Volumetric coverage of the right ventricle (RV) and left ventricles (LV) was obtained using either a breath-held cine balanced steady-state free-precession acquisition or a motion-corrected free-breathing re-binned cine acquisition. Bland-Altman analysis was used to compare LV and RV end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), and LV mass. Diagnostic confidence was scored on a Likert-type ordinal scale by blinded readers.

resultsThere were no significant differences in LV and RV EDV between the two scanners (e.g., LVEDV: p = 0.77, bias = 0.40 mL, correlation coefficient = 0.99; RVEDV: p = 0.17, bias = - 1.6 mL, correlation coefficient = 0.98), and regional wall motion abnormality scoring was similar (kappa 0.99). Blood-myocardium contrast-to-noise ratio (CNR) at 0.55 T was 48 ± 7% of the 1.5 T CNR, and contrast was sufficient for endocardial segmentation in all cases. Diagnostic confidence of images was scored as "good" to "excellent" for the two field strengths in the majority of studies.

conclusionA high-performance 0.55 T system offers good bSSFP CMR image quality, and quantification of biventricular volumes and systolic function that is comparable to 1.5 T in patients.

trial registrationClinicaltrials.gov NCT03331380, NCT03581318.

Indexed as

Ventricular Function, LeftVentricular Function, RightAdultCardiomyopathiesCase-Control StudiesFemaleHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle AgedObserver VariationPredictive Value of TestsReproducibility of ResultsStroke VolumeSystoleCardiovascular magnetic resonanceCine functionLow-field MRIVentricular volumes

Identifiers

PMID32423456
PMCPMC7232838
OpenAlexW3028393437

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.