Evidence map›Paper›PMID 32423360›Full record

ArticleInternational journal of surgical pathology2020

Follicular Cholecystitis: Reappraisal of Incidence, Definition, and Clinicopathologic Associations in an Analysis of 2550 Cholecystectomies.

Burcu Saka, Bahar Memis, Ipek Erbarut Seven, Burcin Pehlivanoglu, Serdar Balci, Pelin Bagci, Michelle Reid, Nevra Dursun, Oscar Tapia Escalano, Juan Carlos Roa and 5 more

Open access · greenAbstract read
In one paragraph

Article in International journal of surgical pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 3 countries.

Burcu Saka218502Istanbul Medipol University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-2043-2041
Bahar Memis1371Emory University, Atlanta, GA, USA.
Ipek Erbarut Seven52982Marmara University, Istanbul, Turkey.
Burcin Pehlivanoglu1371Emory University, Atlanta, GA, USA.ORCID https://orcid.org/0000-0001-6535-8845
Serdar Balci1371Emory University, Atlanta, GA, USA.ORCID https://orcid.org/0000-0002-7852-3851
Pelin Bagci52982Marmara University, Istanbul, Turkey.
Michelle Reid1371Emory University, Atlanta, GA, USA.
Nevra DursunIstanbul Research and Training Hospital, Istanbul, Turkey.
Oscar Tapia EscalanoUniversity of La Frontera, Temuco, Chile.
Juan Carlos Roa28033Pontificia Universidad Catolica de Chile, Santiago, Chile.
Juan Carlos ArayaHospital Dr. Hernan Henriquez Aravena, Temuco, Chile.
So Yeon Kong1371Emory University, Atlanta, GA, USA.
Olca BasturkMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Jill KoshiolNational Cancer Institute, National Institutes of Health, Rockville, MD, USA.
N Volkan Adsay52979Koc University, Istanbul, Turkey.
Emory University · USMarmara University · TRHospital Doctor Hernán Henríquez Aravena · CLIstanbul Medipol University · TRKoç University · TRMemorial Sloan Kettering Cancer Center · USNational Institutes of Health · USPontificia Universidad Católica de Chile · CLUniversidad de La Frontera · CL

Funding

Etiology of Biliary Tract CancerZIACP010218 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI KOSHIOL, JILL · 2011 to 2025
$30.4M
Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA CP010218
6 · The paper itself

Abstract

CONTEXT.: Follicular cholecystitis (FC) is a poorly characterized entity. OBJECTIVE.: To determine its frequency/clinicopathologic associations. DESIGN.: A total of 2550 cholecystectomy specimens were examined. Two hundred three of these were consecutive routine cholecystectomies submitted entirely for microscopic examination to determine the relative frequency of incidental pathologies in gallbladders (GBs). The remainder had representative sampling. Underlying conditions were nonobstructive pathologies (1270 nonspecific cholecystitis), obstructive (62 distal biliary tract tumors, 35 primary sclerosing cholangitis, and 31 autoimmune pancreatitis), and neoplastic (n = 949). FC was defined as 3 distinct lymphoid follicles (LFs)/centimeter. RESULTS.: In the GBs totally submitted for microscopic examination, the true frequency of FC was found to be 2.5% (5/203), and in the representatively sampled group, it was 1.9%, with similar frequencies in nonobstructive, obstructive, and neoplastic cases (2.3%, 3.1%, and 1.3%, respectively, CONCLUSIONS.: Follicular cholecystitis is seen in 2% of cholecystectomies, typically in significantly older patients, suggesting a deranged immune response. A third of the patients reveal biopsy-proven gastritis. FC does not seem to be associated with autoimmunity, lymphoma, or obstructive pathologies.

Indexed as

AgedCholecystectomyCholecystitisCohort StudiesFemaleGallbladderHumansIncidenceMaleMiddle AgedTertiary Lymphoid Structurescholecystectomyfollicular cholecystitishistology

Identifiers

PMID32423360
PMCPMC12355799
OpenAlexW3027943128

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.