Evidence map›Paper›PMID 32423139›Full record

ReviewBiomolecules2020

Unfavorable Effects of Peritoneal Dialysis Solutions on the Peritoneal Membrane: The Role of Oxidative Stress.

Stefanos Roumeliotis, Evangelia Dounousi, Marios Salmas, Theodoros Eleftheriadis, Vassilios Liakopoulos

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Article
  3. Kidney replacement therapy trajectories of patients with kidney failure: an ERA Registry study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
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  10. Article
  11. Article
  12. Review
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  14. Article
  15. Article
  16. Review
  17. Article
  18. [Knowledge and quality of life in chronic kidney disease and peritoneal dialysis].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  19. Analysis of risk factor for peritonitis in peritoneal dialysis patients.American journal of translational research · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Stefanos RoumeliotisDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Evangelia DounousiDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.
Marios SalmasDepartment of Anatomy, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Theodoros EleftheriadisDepartment of Nephrology, University Hospital of Larissa, 41110 Larissa, Greece.ORCID 0000-0001-9302-1633
Vassilios LiakopoulosDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0002-7564-2724
Aristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GRUniversity Hospital of Larissa · GRUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the main limitations to successful long-term use of peritoneal dialysis (PD) as a renal replacement therapy is the harmful effects of PD solutions to the structure and function of the peritoneal membrane (PM). In PD, the PM serves as a semipermeable membrane that, due to exposure to PD solutions, undergoes structural alterations, including peritoneal fibrosis, vasculopathy, and neoangiogenesis. In recent decades, oxidative stress (OS) has emerged as a novel risk factor for mortality and cardiovascular disease in PD patients. Moreover, it has become evident that OS plays a pivotal role in the pathogenesis and development of the chronic, progressive injury of the PM. In this review, we aimed to present several aspects of OS in PD patients, including the pathophysiologic effects on the PM, clinical implications, and possible therapeutic antioxidant strategies that might protect the integrity of PM during PD therapy.

Indexed as

Oxidative StressAnimalsDialysis SolutionsEpithelial CellsGlycation End Products, AdvancedHumansPeritoneal DialysisPeritoneumDialysis SolutionsGlycation End Products, Advancedglucose degradation productsoxidative stressperitoneal dialysisperitoneal membranereactive oxygen species

Identifiers

PMID32423139
PMCPMC7277773
OpenAlexW3024195676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.