Evidence map›Paper›PMID 32422974›Full record

ArticleInternational journal of molecular sciences2020

Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer.

Maja Ludvigsen, Louise Thorlacius-Ussing, Henrik Vorum, Mary Pat Moyer, Mogens Tornby Stender, Ole Thorlacius-Ussing, Bent Honoré

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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  14. Large-Scale Protein Analysis of Experimental Retinal Artery Occlusion.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Maja LudvigsenDepartment of Clinical Medicine, Aarhus University Hospital, Aarhus, DK-8200 Aarhus N, Denmark.ORCID 0000-0001-5089-3271
Louise Thorlacius-UssingDepartment of Biomedicine, Aarhus University, Aarhus, DK-8000 Aarhus C, Denmark.
Henrik VorumDepartment of Clinical Medicine, Aalborg University, Aalborg, DK-9000 Aalborg, Denmark.
Mary Pat MoyerINCELL Corporation, LLC, San Antonio, TX 78249, USA.
Mogens Tornby StenderDepartment of Gastrointestinal Surgery, Aalborg University Hospital, Aalborg, DK-9000 Aalborg, Denmark.
Ole Thorlacius-UssingDepartment of Gastrointestinal Surgery, Aalborg University Hospital, Aalborg, DK-9000 Aalborg, Denmark.
Bent HonoréDepartment of Biomedicine, Aarhus University, Aarhus, DK-8000 Aarhus C, Denmark.ORCID 0000-0002-3459-7429
Aalborg University Hospital · DKAarhus University · DKAarhus University Hospital · DKIncell Corporation (United States) · US

Funding

A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal NABagger-Sørensen Fonden NAHarboefonden NAJohn and Birthe Meyer Foundation NAResearch Foundation of North Jutland Region NA
6 · The paper itself

Abstract

In the western world, colorectal cancer (CRC) is the third most common cause of cancer-related deaths. Survival is closely related to the stage of cancer at diagnosis striking the clinical need for biomarkers capable of early detection. To search for possible biological parameters for early diagnosis of CRC we evaluated protein expression for three CREC (acronym:

Indexed as

AgedAged, 80 and overBiomarkers, TumorCalcium-Binding ProteinsCell Cycle ProteinsColorectal NeoplasmsDNA-Binding ProteinsFemaleGene Expression Regulation, NeoplasticHCT116 CellsHistone ChaperonesHumansIntestinal MucosaMaleMiddle AgedProteomeBiomarkers, TumorCalcium-Binding ProteinsCALU protein, humanCell Cycle ProteinsDNA-Binding ProteinsHistone ChaperonesProteomereticulocalbinS100A6 protein, humanS100 Calcium Binding Protein A6SET protein, humanbiomarkerscellular model systemcolorectal adenocarcinomacolorectal cancerprotein expressionproteomics

Identifiers

PMID32422974
PMCPMC7278953
OpenAlexW3024183110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.