Evidence map›Paper›PMID 32422932›Full record

ArticleViruses2020

Detection of Recombinant Rousettus Bat Coronavirus GCCDC1 in Lesser Dawn Bats (

Adrian C Paskey, Justin H J Ng, Gregory K Rice, Wan Ni Chia, Casandra W Philipson, Randy J H Foo, Regina Z Cer, Kyle A Long, Matthew R Lueder, Xiao Fang Lim and 8 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Establishment of a Captive Cave Nectar Bat (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
  5. Article
  6. Article
  7. Full GenomeFrontiers in public health · 2022
    Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Adrian C PaskeyDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Justin H J NgProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Gregory K RiceGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Wan Ni ChiaProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Casandra W PhilipsonGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Randy J H FooProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Regina Z CerGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Kyle A LongGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Matthew R LuederGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Xiao Fang LimProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Kenneth G FreyGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Theron HamiltonGenomics and Bioinformatics Department, Biological Defense Research Directorate, Naval Medical Research Center-Frederick, Fort Detrick, MD 21702, USA.
Danielle E AndersonProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Eric D LaingDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Ian H MendenhallProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Gavin J SmithProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Lin-Fa WangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Kimberly A Bishop-LillyDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Duke-NUS Medical School · SGLeidos (United States) · USNaval Medical Research Command · USUniformed Services University of the Health Sciences · US

Funding

U.S. Navy Independent Laboratory In house Research (ILIR) Program Virus Detection
6 · The paper itself

Abstract

Rousettus bat coronavirus GCCDC1 (RoBat-CoV GCCDC1) is a cross-family recombinant coronavirus that has previously only been reported in wild-caught bats in Yúnnan, China. We report the persistence of a related strain in a captive colony of lesser dawn bats captured in Singapore. Genomic evidence of the virus was detected using targeted enrichment sequencing, and further investigated using deeper, unbiased high throughput sequencing. RoBat-CoV GCCDC1 Singapore shared 96.52% similarity with RoBat-CoV GCCDC1 356 (NC_030886) at the nucleotide level, and had a high prevalence in the captive bat colony. It was detected at five out of six sampling time points across the course of 18 months. A partial segment 1 from an ancestral Pteropine orthoreovirus, p10, makes up the recombinant portion of the virus, which shares high similarity with previously reported RoBat-CoV GCCDC1 strains that were detected in Yúnnan, China. RoBat-CoV GCCDC1 is an intriguing, cross-family recombinant virus, with a geographical range that expands farther than was previously known. The discovery of RoBat-CoV GCCDC1 in Singapore indicates that this recombinant coronavirus exists in a broad geographical range, and can persist in bat colonies long-term.

Indexed as

AnimalsBetacoronavirusChiropteraCoronavirus InfectionsDisease ReservoirsGenome, ViralGeographyHigh-Throughput Nucleotide SequencingPhylogenyRecombination, GeneticSingaporecoronaviruslesser dawn batrecombinantRousettus bat coronavirus GCCDC1

Identifiers

PMID32422932
PMCPMC7291116
OpenAlexW3024816263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.