Evidence map›Paper›PMID 32422538›Full record

Trial reportDrug and alcohol dependence2020

Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders.

Corey R Roos, Kathleen M Carroll, Charla Nich, Tami Frankforter, Brian D Kiluk

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects of behavioral interventions on stress reactivity in adults with substance use disorders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
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  8. Psychosocial Interventions for Alcohol Use Disorder: A Review of Efficacy, Mechanisms, and Clinical Implications.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Corey R RoosYale University School of Medicine, New Haven, CT, 06510, United States. Electronic address: corey.roos@yale.edu.
Kathleen M CarrollYale University School of Medicine, New Haven, CT, 06510, United States.
Charla NichYale University School of Medicine, New Haven, CT, 06510, United States.
Tami FrankforterYale University School of Medicine, New Haven, CT, 06510, United States.
Brian D KilukYale University School of Medicine, New Haven, CT, 06510, United States.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Efficacy and Mechanisms of CBT4CBT for Alcohol Use DisordersR01AA024122 · NIAAA · YALE UNIVERSITY · PI KILUK, BRIAN D. · 2016 to 2020
$2.7M
Integrating Cognitive Neuroscience Toward Understanding of Mechanisms of CBT for Alcohol Use DisordersK02AA027300 · NIAAA · YALE UNIVERSITY · PI KILUK, BRIAN D. · 2019 to 2023
$719k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K02 AA027300NIAAA NIH HHS R01 AA024122NIDA NIH HHS T32 DA007238
6 · The paper itself

Abstract

backgroundNo studies have examined long-term changes in substance-related coping skills as a statistical mediator of cognitive-behavioral therapy (CBT) for substance use disorders (SUD).

methodsWe tested both short- and long-term changes in coping as mediators of treatment effects in two trials of in-person and/or computerized CBT for SUD. The first trial included 137 individuals (75 % male; 65.7 % non-White; mean age = 35.9) with drug and/or alcohol use disorders randomized to one of the following: in-person CBT, computer-delivered CBT (CBT4CBT) plus brief monitoring, or treatment-as-usual (TAU). The second trial included 68 individuals (65 % male; 66.2 % non-white; mean age = 42.7) with an alcohol use disorder randomized to one of the following: CBT4CBT plus brief monitoring, CBT4CBT plus TAU, or TAU only. Coping was assessed with the Coping Strategies Scale. Latent growth curve mediational models were conducted, with both short-term (baseline through end-of-treatment) and long-term (baseline through 3-month post-treatment follow-up) changes in coping.

resultsThere were no mediation effects for short-term changes in coping. However, in both trials, there were significant mediation effects for long-term changes in coping: In trial 1, the effect of CBT4CBT vs. TAU on substance use at the 6-month follow-up was mediated by long-term increases in coping. This same mediation effect was not found for in-person CBT vs. TAU. In trial 2, the effect of CBT4CBT vs. not receiving CBT4CBT on heavy drinking at the 6-month follow-up was mediated by long-term increases in coping.

conclusionsLong-term increases in coping may be a mechanism of change in computerized CBT for SUD.

Indexed as

Adaptation, PsychologicalAdultCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedSubstance-Related DisordersTherapy, Computer-AssistedTime FactorsTreatment OutcomeCognitive-behavioral therapyCoping skillsMechanisms of changeMediatorSubstance use disorders

Identifiers

PMID32422538
PMCPMC7293942
OpenAlexW3024142983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.