ArticlePloS one2020
Temperature and preeclampsia: Epidemiological evidence that perturbation in maternal heat homeostasis affects pregnancy outcome.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- A systematic review and meta-analysis on heat thresholds for maternal health and birth outcomes.Nature communications · 2026Pooled it
- Impacts of heat exposure in utero on long-term health and social outcomes: a systematic review.BMC pregnancy and childbirth · 2024Pooled it
- Impact of ambient heat exposure on pregnancy outcomes in low- and middle-income countries: A systematic review.Women's health (London, England)Pooled it
- Postpartum depression and quality of life in the first year after childbirth: ethnic differences.Social psychiatry and psychiatric epidemiology · 2026Article
- Prolactin receptor signalling contributes to the attenuation of stress-induced hyperthermia during pregnancy.Journal of neuroendocrinology · 2026Article
- Association between first trimester ambient temperature and the risk of gestational hypertension and pre-eclampsia: Insights from the PRECISE study cohort in The Gambia, Kenya and Mozambique.Research square · 2026Article
- The Impact of Ambient Heat on Perinatal and Neonatal Health in the Context of Climate Change: A Scoping Review.Current environmental health reports · 2026Article
- Association between climate change awareness and psychological distress among Turkish pregnant women: A cross-sectional study.Medicine · 2026Article
- Exploring climate-related health risks and behaviors among vulnerable populations in the eastern Mediterranean: the cases of Jewish and Bedouin Negev desert residents.Frontiers in public health · 2026Article
- Toward climate resilience in Israel's healthcare system: decision-makers' perspectives.Israel journal of health policy research · 2025Article
- Cultural Adaptation and One-Year Follow-Up of the Mom-to-Mom Program Among Minority Arab Bedouin Women: Addressing Postpartum Depression.Journal of clinical medicine · 2025Article
- Identifying the impact and critical windows of extreme temperatures on the risk of gestational diabetes mellitus in twin pregnancies.Journal of endocrinological investigation · 2025Article
- In utero exposure to extreme heat increases neonatal mortality.PNAS nexus · 2025Article
- Variability in the Length of Stay and Daily Medical Expenses in Inpatient Care in Korea, 2010-2019: Hypertension and Pneumonia.Journal of Korean medical science · 2025Article
- The Influence of Heat on Pediatric and Perinatal Health: Risks, Evidence, and Future Directions.Journal of clinical medicine · 2025Review
- Prenatal exposure to heat and humidity and infant birth size in Ghana.Environmental research · 2025Article
- Scoping review of climate drivers on maternal health: current evidence and clinical implications.AJOG global reports · 2025Review
- A time-stratified, case-crossover study of heat exposure and perinatal mortality from 16 hospitals in sub-Saharan Africa.Nature medicine · 2024Article
- Article
- Ambient temperature-related sex ratio at birth in historical urban populations: the example of the city of Poznań, 1848-1900.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study aims to determine the association between temperature and preeclampsia and whether it is affected by seasonality and rural/urban lifestyle.
methodsThis cohort study included women who delivered at our medical center from 2004 to 2013 (31,101 women, 64,566 deliveries). Temperature values were obtained from a spatiotemporally resolved estimation model performing predictions at a 1×1km spatial resolution. In "Warm" pregnancies >50% of gestation occurred during the spring-summer period. In cold pregnancies >50% of gestation occurred during the fall and winter. Generalized estimating equation multivariable models were used to estimate the association between temperature and incidence of preeclampsia.
results1) The incidence of preeclampsia in at least one pregnancy was 7% (2173/64,566); 2) during "warm" pregnancies, an elevation of one IQR of the average temperature in the 1st or the 3rd trimesters was associated with an increased risk to develop preeclampsia [patients with Jewish ethnicity: 1st trimester: relative risk (RR) of 2.38(95%CI 1.50; 3.80), 3rd trimester 1.94(95%CI 1.34;2.81); Bedouins: 1st trimester: RR = 2.91(95%CI 1.98;4.28), 3rd trimester: RR = 2.37(95%CI 1.75;3.20)]; 3) In "cold" pregnancies, an elevation of one IQR of average temperature was associated with a lower risk to develop preeclampsia among patients with Bedouin-Arab ethnicity RR = 0.68 (95% CI 0.49-0.94) for 1st trimester and RR = 0.62 (95% CI 0.44-0.87) for 3rd trimester.
conclusions1) Elevated averaged temperature during the 1st or 3rd trimesters in "warm" pregnancies confer an increased risk for the development of preeclampsia, especially in nomadic patients; 2) Of interest, during cold pregnancies, elevated averaged temperature was associated with a lower risk to develop preeclampsia for nomadic patients. 3) These findings suggest temperature might be associated with perturbations in maternal heat homeostasis resulting in reallocation of energy resources and their availability to the fetus that may increase the risk for preeclampsia. This observation is especially relevant in the context of global warming and its effects on maternal/fetal reproductive health.
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