Evidence map›Paper›PMID 32421595›Full record

ArticleJournal of affective disorders2020

Affective Processing Biases in Relation to Past, Current, and Future Depression in Children and Adolescents.

Taban Salem, Mary A Fristad, L Eugene Arnold, H Gerry Taylor, Thomas W Frazier, Sarah M Horwitz, Robert L Findling, The Lams Group

Abstract read
In one paragraph

Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Taban SalemDepartment of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH. Electronic address: taban.salem@osumc.edu.
Mary A FristadDepartment of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH; Departments of Psychology and Nutrition, The Ohio State University, Columbus, OH.
L Eugene ArnoldDepartment of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH.
H Gerry TaylorBiobehavioral Health Center, Abigail Wexner Research Institute at Nationwide Children's Hospital, and Department of Pediatrics, The Ohio State University, Columbus, OH.
Thomas W FrazierAutism Speaks, New York, NY.
Sarah M HorwitzDepartment of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY.
Robert L FindlingDepartment of Psychiatry, Virginia Commonwealth University, Richmond, VA.
The Lams GroupDepartment of Psychiatry, Division of Child and Adolescent Psychiatry, Case Western Reserve University, Cleveland, OH; and Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA; and Division of Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Funding

Longitudinal Assessment of Manic SymptomsR01MH073967 · NIMH · JOHNS HOPKINS UNIVERSITY · PI FINDLING, ROBERT L · 2005 to 2016
$11.4M
Longitudinal Assessment of Manic Symptoms (LAMS)R01MH073953 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS, PHILLIPS, MARY LOUISE · 2005 to 2016
$8.7M
Longitudinal Assessment of Manic Symptoms (LAMS)R01MH073816 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI HOLLAND, SCOTT K. · 2005 to 2016
$5.9M
Longitudinal Assessment of Manic Symptoms (LAMS) StudyR01MH073801 · NIMH · OHIO STATE UNIVERSITY · PI FRISTAD, MARY A · 2005 to 2016
$5.9M
NIMH NIH HHS R01 MH073801NIMH NIH HHS R01 MH073816NIMH NIH HHS R01 MH073953NIMH NIH HHS R01 MH073967
6 · The paper itself

Abstract

backgroundThe affective go/no-go (AGN) task has been used to assess affective biases in attention set-shifting and deficits in inhibitory control of emotional information among depressed youth, but results have been inconsistent. We aimed to test AGN robustness and clarify temporal relationships between depressive symptoms and affective processing in youth.

methodsWe evaluated AGN performance twice (Time 1 N = 306; Time 2 N = 238) in relation to current, previous, and future depression in the same children/adolescents with depression and those without diagnoses who participated in the Longitudinal Assessment of Manic Symptoms (LAMS) study. Mixed repeated ANCOVAs were powered to detect small-medium group by valence interactions in response latency and errors. Supplemental regression analyses examined depressive symptoms as a continuous variable in relation to AGN performance.

resultsNo clear pattern emerged, mirroring the broader AGN literature. In primary analyses, group by valence interactions were only observed at one AGN administration; none replicated across administrations. Similarly, in regression analyses depressive symptoms had no relation to affective processing biases/deficits at AGN Time 1, though some relationships were detected between symptoms and AGN Time 2. LIMITATIONS: Relatively few youth met criteria for a depressive disorder, though analyses were appropriately powered and supplemental analyses examined depressive symptoms continuously. Comparison groups were not healthy controls at recruitment but were free from any Axis I disorder at AGN administration.

conclusionsGiven the inconsistency of AGN findings, attention should be focused on tasks that provide more sensitive, robust measures of emotional information processing in depressed youth.

Indexed as

DepressionEmotionsAdolescentAttentionBiasChildHumansReaction TimeAttentional biasChildhood, Adolescence, Emotion processingDepressionInhibitory control

Identifiers

PMID32421595
PMCPMC9261905

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.