ArticleAmerican journal of physiology. Endocrinology and metabolism2020
CTRP12 ablation differentially affects energy expenditure, body weight, and insulin sensitivity in male and female mice.
Article in American journal of physiology. Endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- CTRP10 is required for optimal motor function.The Journal of biological chemistry · 2026Article
- CTRP12 in cardiovascular and metabolic diseases: current status and future perspective.Frontiers in cardiovascular medicine · 2026Review
- Article
- Role of CTRP14/C1QL1 in motor coordination and learning across the lifespan.Physiology & behavior · 2025Article
- Consideration of sex as a biological variable in diabetes research across twenty years.Biology of sex differences · 2024Article
- CTRP12 ameliorates post-myocardial infarction heart failure through down-regulation of cardiac apoptosis, oxidative stress and inflammation by influencing the TAK1-p38 MAPK/JNK pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023Article
- CTRP14 inactivation alters physical activity and food intake response to fasting and refeeding.American journal of physiology. Endocrinology and metabolism · 2022Article
- CTRP11 contributes modestly to systemic metabolism and energy balance.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Article
- CTRP6 rapidly responds to acute nutritional changes, regulating adipose tissue expansion and inflammation in mice.American journal of physiology. Endocrinology and metabolism · 2021Article
- CTRP4 ablation impairs associative learning and memory.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway.Cell death & disease · 2021Article
- Loss of CTRP4 alters adiposity and food intake behaviors in obese mice.American journal of physiology. Endocrinology and metabolism · 2020Article
- CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression.FEBS letters · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Secreted hormones facilitate tissue cross talk to maintain energy balance. We previously described C1q/TNF-related protein 12 (CTRP12) as a novel metabolic hormone. Gain-of-function and partial-deficiency mouse models have highlighted important roles for this fat-derived adipokine in modulating systemic metabolism. Whether CTRP12 is essential and required for metabolic homeostasis is unknown. We show here that homozygous deletion of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.