Evidence map›Paper›PMID 32421340›Full record

ArticleJournal of the American Society for Mass Spectrometry2020

Generation of Multiply Charged Protein Anions from Multiply Charged Protein Cations via Gas-Phase Ion/Ion Reactions.

Hsi-Chun Chao, Mack Shih, Scott A McLuckey

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026
    Review
  2. Review
  3. Article
  4. Recent Advances in Gas-phase Ion/Ion Chemistry for Lipid Analysis.Trends in analytical chemistry : TRAC · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hsi-Chun ChaoDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
Mack ShihDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
Scott A McLuckeyDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.ORCID http://orcid.org/0000-0002-1648-5570

Funding

Gas-phase Bio-conjugation in the Tandem Mass Spectrometry of Peptides, Proteins,R37GM045372 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2014 to 2023
$3.1M
NIGMS NIH HHS R37 GM045372
6 · The paper itself

Abstract

We report a novel charge inversion ion/ion reaction that converts multiply charged protein cations to multiply charged protein anions via a single ion/ion collision using highly charged anions derived from nanoelectrospray ionization (nESI) of hyaluronic acids (HAs). This type of charge inversion reaction is demonstrated with cations derived from cytochrome

Indexed as

AnionsCationsGasesHyaluronic AcidProteinsSpectrometry, Mass, Electrospray IonizationAnionsCationsGasesHyaluronic AcidProteinscharge inversionhyaluronic acid anionsion/ion chemistrymultiply charged ions

Identifiers

PMID32421340
PMCPMC7332380

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.