Evidence map›Paper›PMID 32421034›Full record

ArticleAdvanced synthesis & catalysis2020

Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω-Transaminases.

Wesley Böhmer, Alexey Volkov, Karim Engelmark Cassimjee, Francesco G Mutti

Open access · hybridAbstract read
In one paragraph

Article in Advanced synthesis & catalysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Wesley BöhmerVan't Hoff Institute for Molecular Sciences, HIMS-Biocat University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.
Alexey VolkovEnginZyme AB Tomtebodavägen 6 171 65 Solna Sweden.
Karim Engelmark CassimjeeEnginZyme AB Tomtebodavägen 6 171 65 Solna Sweden.
Francesco G MuttiVan't Hoff Institute for Molecular Sciences, HIMS-Biocat University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.
EnginZyme (Sweden) · SEUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compared with biocatalysis in aqueous media, the use of enzymes in neat organic solvents enables increased solubility of hydrophobic substrates and can lead to more favorable thermodynamic equilibria, avoidance of possible hydrolytic side reactions and easier product recovery. ω-Transaminases from

Indexed as

asymmetric synthesisbiocatalysisflow chemistrytransaminasesα-chiral amines

Identifiers

PMID32421034
PMCPMC7217232
OpenAlexW3000798026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.