ReviewActa bio-medica : Atenei Parmensis2020
Assessment and treatment of older individuals with COVID 19 multi-system disease: Clinical and ethical implications.
Review in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis.European radiology · 2022Pooled it
- Prevalence and risk factors for post-COVID-19 syndrome on medical students in Tabuk, Saudi Arabia-2023-2024.Journal of family medicine and primary care · 2025Article
- Safety and Efficacy of Paxlovid Against Omicron Variants of Coronavirus Disease 2019 in Elderly Patients.Infectious diseases and therapy · 2023Article
- An atypical presentation of COVID-19: Hidden risk for seniors to misdiagnose.Northern clinics of Istanbul · 2023Article
- The implications of COVID-19 on health and social care personnel in long-term care facilities for older people: An international scoping review.Health & social care in the community · 2022Article
- COVID-19 inflammation and implications in drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2022Review
- Apocalyptic COVID-19 mortality and BMI: a J-shape relationship?Acta bio-medica : Atenei Parmensis · 2022Article
- Green Synthesis-Mediated Nanoparticles and Their Curative Character Against Post COVID-19 Skin Diseases.Current pharmacology reports · 2022Review
- Coronavirus Disease 2019.Clinics in geriatric medicine · 2021Review
- COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study.Infection · 2021Observational
- Clinical, biological and radiological features, 4-week outcomes and prognostic factors in COVID-19 elderly inpatients.Infectious diseases now · 2021Article
- Longitudinal Metabolomics Reveals Ornithine Cycle Dysregulation Correlates With Inflammation and Coagulation in COVID-19 Severe Patients.Frontiers in microbiology · 2021Article
- Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities.Age and ageing · 2020Review
- Updates on laboratory investigations in coronavirus disease 2019 (COVID-19).Acta bio-medica : Atenei Parmensis · 2020Review
- Investigation of SARS-CoV-2 outbreaks in six care homes in London, April 2020.EClinicalMedicine · 2020Article
- Multimorbidity patterns among COVID-19 deaths: proposal for the construction of etiological models.Revista panamericana de salud publica = Pan American journal of public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Covid-19 infection is a multisystem disease more frequent in older individuals, especially in those with multiple chronic diseases. This multimorbid and frail population requires attention and a personalized comprehensive assessment in order to avoid the occurrence of adverse outcomes. As other diseases, the COVID-19 presentation in older patients is often atypical with less severe and unspecific symptoms. These subjects both at home and during hospitalization suffer isolation and the lack of support of caregivers. The geriatric care in COVID-19 wards is often missing. The application of additional instruments would be necessary to facilitate and personalize the clinical approach, not only based on diseases but also on functional status. This narrative review starts from diagnostic evaluation, continues with adapted pharmacologic treatment and ends with the recovery phase targeting the nutrition and physical exercise. We developed a check-list of respiratory, gastro-intestinal and other less-specific symptoms, summarized in a table and easily to be filled-up by patients, nurses and general practitioners. As second step, we reported the clinical phases of this disease. Far to be considered just viral infective and respiratory, this disease is also an inflammatory and thrombotic condition with frequent bacterial over-infection. We finally considered timing and selection of treatment, which depend on the disease phase, co-administration of other drugs and require the monitoring of renal, liver and cardiac function. This underlines the role of age not just as a limitation, but also an opportunity to increase the quality and the appropriateness of multidisciplinary and multidimensional intervention in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.