ArticleeLife2020
ER-luminal [Ca
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- The Genetics of TDP-43 Type C Neurodegeneration: A Whole-Genome Sequencing Study and Literature Review.Neurology. Genetics · 2026Article
- Structural dynamics of adenine nucleotide potentiation of the human type 2 IPbioRxiv : the preprint server for biology · 2026Article
- One-step Immobilization of Human α-1-acid Glycoprotein on Magnetic Beads: A Rapid Method for Small Molecule hAGP Binding Study.The AAPS journal · 2025Article
- STIM-IP3R crosstalk regulates migration of breast cancer cells.The Journal of cell biology · 2025Article
- Stochastic model of IP3-induced Ca2+ spiking of HEK293 cells.PLoS computational biology · 2025Article
- Reciprocal rescue of Wolfram syndrome by two causative genes.EMBO reports · 2025Article
- Biological physics to uncover cell signaling.Biophysical reviews · 2025Review
- Annexin- and calcium-regulated priming of legume root cells for endosymbiotic infection.Nature communications · 2024Article
- Quantitative proteomics reveals the mechanism of endoplasmic reticulum stress-mediated pulmonary fibrosis in mice.Heliyon · 2024Article
- The ion channels of endomembranes.Physiological reviews · 2024Review
- Agonist-Induced CaCells · 2024Article
- Structural titration reveals CaNature communications · 2023Article
- Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation.Pflugers Archiv : European journal of physiology · 2023Article
- Dissociation of inositol 1,4,5-trisphosphate from IPThe Journal of biological chemistry · 2023Article
- Annexin A1 exerts renoprotective effects in experimental crescentic glomerulonephritis.Frontiers in physiology · 2022Article
- Termination of CaCell calcium · 2021Article
- Quantal CaCell reports · 2021Article
- KRAP tethers IPNature communications · 2021Article
- Deletion of TRPV3 and CaV3.2 T-type channels in mice undermines fertility and Ca2+ homeostasis in oocytes and eggs.Journal of cell science · 2021Article
- In the Right Place at the Right Time: Regulation of Cell Metabolism by IP3R-Mediated Inter-Organelle CaFrontiers in cell and developmental biology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Horia VaisDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Min WangDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Karthik MallilankaramanDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-9492-9050
Riley PayneDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Chris McKennanDepartment of Statistics, University of Pittsburgh, Pittsburgh, United States.
Jeffrey T LockDepartment of Neurobiology and Behavior, University of California, Irvine, United States.ORCID 0000-0003-1522-3189
Lynn A SpruceProteomics Core Facility, The Children's Hospital of Philadelphia, Philadelphia, United States.
Carly FiestDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-1162-712X
Matthew Yan-Lok ChanDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Ian ParkerDepartment of Neurobiology and Behavior, University of California, Irvine, United States.
Steven H SeeholzerProteomics Core Facility, The Children's Hospital of Philadelphia, Philadelphia, United States.
J Kevin FoskettDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-8854-0268
Don-On Daniel MakDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0001-7869-9382
University of Pennsylvania · USChildren's Hospital of Philadelphia · USUniversity of California, Irvine · USUniversity of Pittsburgh · US
Funding
Elementary Events of Intracellular Calcium SignalingR37GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 2011 to 2020
$5.3MElectrophysiology of nuclear membrane InsP3 receptorR37GM056328 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2011 to 2020
$4.9MSPATIAL AND TEMPORAL ASPECTS OF INSP3 SIGNALLINGR01GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 1992 to 2010
$3.9MMolecular physiology of intracellular InsP3R and MCU ion channelsR35GM140975 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2021 to 2025
$2.2MMolecular mechanisms of ER luminal [Ca2+] modulation of InsP3R channel activityR01GM114042 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MAK, DON-ON DANIEL · 2016 to 2019
$1.4MNIGMS NIH HHS R01 GM048071NIGMS NIH HHS R01 GM114042NIGMS NIH HHS R35 GM140975NIGMS NIH HHS R37 GM048071NIGMS NIH HHS R37 GM056328
Abstract
Modulating cytoplasmic Ca
Indexed as
A549 CellsAnimalsAnnexin A1CalciumCalcium-Binding ProteinsCalcium SignalingCell Line, TumorCell Physiological PhenomenaChickensEndoplasmic ReticulumHEK293 CellsHumansInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsIon Channel GatingMiceAnnexin A1CalciumCalcium-Binding ProteinsInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate Receptorsannexincalcium signalingendoplasmic reticulum lumeninositol 1,4,5-trisphosphate receptorintracellular calcium-release channelmolecular biophysicsnonesingle-channel gating regulationstructural biology
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.