Evidence map›Paper›PMID 32420873›Full record

ArticleeLife2020

MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning.

Ying Zhang, Yi Zhu, Shu-Xia Cao, Peng Sun, Jian-Ming Yang, Yan-Fang Xia, Shi-Ze Xie, Xiao-Dan Yu, Jia-Yu Fu, Chen-Jie Shen and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Optimized Administration of the MACS chemical neuroscience · 2022
    Article
  8. Article
  9. Clinical and Preclinical Evidence for MNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Article
  10. Chemogenetics as a neuromodulatory approach to treating neuropsychiatric diseases and disorders.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  11. Threat and Bidirectional Valence Signaling in the Nucleus Accumbens Core.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Ying Zhang *Center for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yi Zhu *Center for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-4273-0955
Shu-Xia Cao *Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Peng SunCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jian-Ming YangCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yan-Fang XiaCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shi-Ze XieCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiao-Dan YuCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jia-Yu FuCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chen-Jie ShenCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hai-Yang HeCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hao-Qi PanCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiao-Juan ChenCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hao WangCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiao-Ming LiCenter for Neuroscience and Department of Neurology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-8617-1702
Second Affiliated Hospital of Zhejiang University · CNSir Run Run Shaw Hospital · CNUniversity of Toronto · CA

Funding

Funds for Creative Research Groups of China from the National Natural Science Foundation of China 81521062Guangdong Science and Technology Department 2018B030334001Key Project of the National Natural Science Foundation of China 31430034Key Realm R&D Prgram of Guangdong Province 2019B030335001Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences 2019PT310023The National Key Research and Development Plan of Ministry of Science and Technology of China 2016YF051000
6 · The paper itself

Abstract

Methyl-CpG-binding protein 2 (MeCP2) encoded by the

Indexed as

AnimalsCholinergic NeuronsDisease Models, AnimalFearInterneuronsLearningMethyl-CpG-Binding Protein 2MiceMice, Inbred C57BLMice, KnockoutNucleus AccumbensReceptors, GABA-ARNA InterferenceMecp2 protein, mouseMethyl-CpG-Binding Protein 2Receptors, GABA-Acholinergic interneuronsfear learningGABAA α2 receptorMeCP2mouseneurosciencenucleus accumbens

Identifiers

PMID32420873
PMCPMC7259956
OpenAlexW3027905648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.