ArticleeLife2020
Retrieval practice facilitates memory updating by enhancing and differentiating medial prefrontal cortex representations.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Enhanced episodic memory and LTP-like plasticity in subjective cognitive decline following 10-Hz repetitive transcranial magnetic stimulation.Journal of neuroengineering and rehabilitation · 2025Trial
- Recitation Mode Is Associated With Salivary CREB and Cortisol Responses during Qur'anic Recitation.Brain and behavior · 2026Article
- Condition-specific neural signatures of reactivation during post-retrieval rest: An EEG study.iScience · 2026Article
- A large-scale heterogeneous 3D magnetic resonance brain imaging dataset for self-supervised learning.Scientific data · 2026Article
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- An integrated behavioral neuroscience and educational psychology curriculum enhances medical interns' engagement, resilience, and clinical performance in Saudi Arabia.Frontiers in medicine · 2026Article
- Neural correlates and reinstatement of recent and remote memory in children and young adults.eLife · 2025Article
- The role of memory in affirming-the-consequent fallacy.iScience · 2025Article
- Article
- Distinct roles of excitatory and inhibitory neurons in the medial prefrontal cortex in the expression and reconsolidation of methamphetamine-associated memory in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Goal-directed attention transforms both working and long-term memory representations in the human parietal cortex.PLoS biology · 2024Article
- Contextual memory engrams, and the neuromodulatory influence of the locus coeruleus.Frontiers in molecular neuroscience · 2024Review
- Intersubject similarity in neural representations underlies shared episodic memory content.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Associating the old with the new.eLife · 2022Article
- Article
- Transformative neural representations support long-term episodic memory.Science advances · 2021Article
- Transforming the Concept of Memory Reactivation.Trends in neurosciences · 2020Review
- Article
- Phase similarity between similar objects indicates representational merging across retrieval training but not sleep.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Updating old memories with new, more current information is critical for human survival, yet the neural mechanisms for memory updating in general and the effect of retrieval practice in particular are poorly understood. Using a three-day A-B/A-C memory updating paradigm, we found that compared to restudy, retrieval practice could strengthen new A-C memories and reduce old A-B memory intrusion, but did not suppress A-B memories. Neural activation pattern analysis revealed that compared to restudy, retrieval practice led to stronger target representation in the medial prefrontal cortex (MPFC) during the final test. Critically, it was only under the retrieval practice condition that the MPFC showed strong and comparable competitor evidence for both correct and incorrect trials during final test, and that the MPFC target representation during updating was predictive of subsequent memory. These results suggest that retrieval practice is able to facilitate memory updating by strongly engaging MPFC mechanisms in memory integration, differentiation and consolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.