Evidence map›Paper›PMID 32420793›Full record

ArticleHuman vaccines & immunotherapeutics2020

Early impact of the Australian national shingles vaccination program with the herpes zoster live attenuated vaccine.

John Litt, Robert Booy, Debra Bourke, Dominic E Dwyer, Alan Leeb, Philip McCloud, Alicia N Stein, Michael Woodward, Anthony L Cunningham

Open access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

John LittDiscipline of General Practice College of Medicine and Public Health, Flinders University , Adelaide, Australia.
Robert BooyNational Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The University of Sydney , Sydney, Australia.
Debra BourkeMedical Department, Seqirus (Australia) Pty Ltd , Parkville, Australia.
Dominic E DwyerNSW Health Pathology - Institute for Clinical Pathology and Medical Research, Westmead Hospital and the University of Sydney , Sydney, Australia.
Alan LeebIllawarra Medical Centre , Ballajura, Australia.
Philip McCloudMcCloud Consulting Group , Belrose, Australia.
Alicia N SteinHelath Economics, Seqirus (Australia) Pty Ltd , Parkville, Australia.
Michael WoodwardCentre for Virus Research, Aged Care Services, Austin Health, University of Melbourne , Melbourne, Australia.
Anthony L CunninghamFaculty of Medicine and Health, The Westmead Institute for Medical Research , Westmead, Australia.ORCID 0000-0002-6744-5667
The University of Sydney · AUFlinders University · AUIllawarra Health and Medical Research Institute · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes zoster (shingles) is a painful condition resulting from reactivation of latent varicella zoster virus (VZV). The Australian National Shingles Vaccination Program (commenced November 2016) provides free herpes zoster vaccination for eligible adults aged 70 years, with a 5-year catch-up program (until October 2021) for adults aged 71-79 years. Patterns and impact of the program were evaluated by analysis of vaccine distribution and delivery data and specific antiviral prescription data from the Pharmaceutical Benefits Scheme. During the first 2 years, uptake of funded live attenuated shingles vaccine ZOSTAVAX® (Zoster Virus Vaccine Live; ZVL) was high across the ongoing and catch-up programs. Before program implementation (2006-2016), herpes zoster coded antiviral prescription rates increased by 2.2% per year (95% CI: 1.5, 2.9) in the 70-79 years age group. In the two years since program launch, herpes zoster antiviral prescription rates declined substantially in this age group, by an average of 13.6% per year (95% CI: 1.5, 24.2). These results indicate that the National Shingles Vaccination Program has been highly successful in vaccinating a considerable proportion of Australian adults aged 70-79 years against herpes zoster and suggest that vaccine uptake was associated with decreased incidence of herpes zoster.

Indexed as

Herpes ZosterHerpes Zoster VaccineNeuralgia, PostherpeticVaccines, AttenuatedAdultAgedAustraliaHerpesvirus 3, HumanHumansVaccinationHerpes Zoster VaccineVaccines, AttenuatedHerpes zosterherpes zoster vaccinepostherpetic neuralgiashinglesvaricella zoster viruszoster virus vaccine live

Identifiers

PMID32420793
PMCPMC8641585
OpenAlexW3025333655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.