Evidence map›Paper›PMID 32420516›Full record

ArticleBioactive materials2020

Characteristics of novel Ti-10Mo-xCu alloy by powder metallurgy for potential biomedical implant applications.

Wei Xu, Chenjin Hou, Yuxuan Mao, Lei Yang, Maryam Tamaddon, Jianliang Zhang, Xuanhui Qu, Chaozong Liu, Bo Su, Xin Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Review
  3. Application of Copper Nanoparticles in Dentistry.Nanomaterials (Basel, Switzerland) · 2022
    Review
  4. Review
  5. Article
  6. Review
  7. Recent Advances in Research on Antibacterial Metals and Alloys as Implant Materials.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Wei XuBeijing Advanced Innovation Center for Materials Genome Engineering, State Key Laboratory for Advanced Metals and Materials, Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing, China.
Chenjin HouBeijing Advanced Innovation Center for Materials Genome Engineering, State Key Laboratory for Advanced Metals and Materials, Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing, China.
Yuxuan MaoCenter for Health Science and Engineering, Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control Technology, School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300130, China.
Lei YangCenter for Health Science and Engineering, Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control Technology, School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300130, China.
Maryam TamaddonInstitute of Orthopaedic & Musculoskeletal Science, University College London, Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK.
Jianliang ZhangSchool of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing, 100083, China.
Xuanhui QuBeijing Advanced Innovation Center for Materials Genome Engineering, State Key Laboratory for Advanced Metals and Materials, Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing, China.
Chaozong LiuInstitute of Orthopaedic & Musculoskeletal Science, University College London, Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK.
Bo SuBristol Dental School, University of Bristol, Bristol, BS1 2LY, UK.
Xin LuBeijing Advanced Innovation Center for Materials Genome Engineering, State Key Laboratory for Advanced Metals and Materials, Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing, China.
University of Science and Technology Beijing · CNHebei University of Technology · CNRoyal National Orthopaedic Hospital · GBUniversity Of Bristol Dental Hospital · GB

Funding

Medical Research Council MR/N010345/1Medical Research Council MR/S010343/1
6 · The paper itself

Abstract

When biomaterials are implanted in the human body, the surfaces of the implants become favorable sites for microbial adhesion and biofilm formation, causing peri-implant infection which frequently results in the failure of prosthetics and revision surgery. Ti-Mo alloy is one of the commonly used implant materials for load-bearing bone replacement, and the prevention of infection of Ti-Mo implants is therefore crucial. In this study, bacterial inhibitory copper (Cu) was added to Ti-Mo matrix to develop a novel Ti-Mo-Cu alloy with bacterial inhibitory property. The effects of Cu content on microstructure, tensile properties, cytocompatibility, and bacterial inhibitory ability of Ti-Mo-Cu alloy were systematically investigated. Results revealed that Ti-10Mo-1Cu alloy consisted of α and β phases, while there were a few Ti

Indexed as

Bacterial inhibitory propertyCytocompatibilityMechanical propertiesMicrostructureTi-10Mo-xCu alloy

Identifiers

PMID32420516
PMCPMC7218015
OpenAlexW3019170424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.