Evidence map›Paper›PMID 32420406›Full record

ArticleOpen forum infectious diseases2020

Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever.

Risa Fuller, Erin Moshier, Samantha E Jacobs, Douglas Tremblay, Guido Lancman, Alexander Coltoff, Jessica Caro, John Mascarenhas, Meenakshi Rana

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Risa FullerDivision of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0003-3263-166X
Erin MoshierTCI Biostatistics Shared Resource Facility, Institute for Healthcare Delivery Science, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Samantha E JacobsDivision of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Douglas TremblayTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Guido LancmanTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Alexander ColtoffTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Jessica CaroTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
John MascarenhasTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Meenakshi RanaDivision of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Icahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.

Indexed as

acute myeloid leukemiaantimicrobial stewardshipneutropenic fever

Identifiers

PMID32420406
PMCPMC7216765
OpenAlexW3017554704

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.