Evidence map›Paper›PMID 32420402›Full record

ArticleOpen forum infectious diseases2020

Recurrence of

Inke Nadia D Lubis, Hendri Wijaya, Munar Lubis, Chairuddin P Lubis, Khalid B Beshir, Sarah G Staedke, Colin J Sutherland

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02325180 (Clinical Efficacy of Artemisinin-based Combination Therapy for Treatment of Uncomplicated Plasmodium Falciparum Malaria in North Sumatera, Indonesia and the Association of Molecular Markers With Treatment Outcomes), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02325180 phase4completednot on this map

Clinical Efficacy of Artemisinin-based Combination Therapy for Treatment of Uncomplicated Plasmodium Falciparum Malaria in North Sumatera, Indonesia and the Association of Molecular Markers With Treatment Outcomes

TypeinterventionalSponsorLondon School of Hygiene and Tropical MedicineRan2015 to 2015Enrolled338ConditionsMalaria, FalciparumArmsDihydroartemisinin-Piperaquine, Artemether-lumefantrine
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Plasmodium ovale Malaria in Travelers and Immigrants to the United States: A Case Series.The American journal of tropical medicine and hygiene · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Plasmodium falciparum Isolates CarryingAntimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Inke Nadia D LubisDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Hendri WijayaDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Munar LubisDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Chairuddin P LubisDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Khalid B BeshirInfection and Immunity Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Sarah G StaedkeDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Colin J SutherlandInfection and Immunity Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
University of North Sumatra · IDLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe assessed the efficacy of artemisinin-based combination therapies for treatment of uncomplicated

methodsFebrile patients aged >6 months with uncomplicated

resultsOf the 3731 participants screened, 302 were enrolled and randomized. In the dihydroartemisinin-piperaquine arm,

conclusionsIn Sumatera, both regimens effectively cleared initial parasitemia, but

trial registrationNCT02325180.

Indexed as

artemisinin combination therapyin vivo drug efficacymultispecies malaria infections

Identifiers

PMID32420402
PMCPMC7216766
OpenAlexW3014391325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.