Evidence map›Paper›PMID 32420357›Full record

Trial reportBioMed research international2020

KIR3DL1 and HLA-Bw4 Interaction Showed a Favorable Role in Patients with Myelodysplastic Syndromes in Chinese Southern Han.

Jian Xin Zhen, Si Qi Cai, Yuan Tao Chen, Zhi Chao Yang, Jia Cai Zhuo, Zhi Hui Deng

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jian Xin ZhenCentral Laboratory, Shenzhen Baoan Women's and Children's Hospital, Shenzhen, Guangdong 518102, China.
Si Qi CaiImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong 518035, China.
Yuan Tao ChenDepartment of Biology, College of Arts & Sciences, University of Virginia, Charlottesville, VA 22904, USA.
Zhi Chao YangImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong 518035, China.
Jia Cai ZhuoDepartment of Hematology, Shenzhen Second People's Hospital, Shenzhen, Guangdong 518034, China.
Zhi Hui DengImmunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong 518035, China.ORCID https://orcid.org/0000-0002-2046-1467
Shenzhen Blood Center · CNShenzhen Bao'an District People's Hospital · CNShenzhen Second People's Hospital · CNUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association studies of killer cell immunoglobulin-like receptors (KIRs) with the occurrence of myelodysplastic syndromes (MDS) are limited worldwide; this study investigated the genetic risk/protective factors of MDS in KIR and human leucocyte antigen (HLA) systems to gain a better understanding of the role played by KIR and their cognate HLA ligands in MDS pathogenesis.

methodsWe genotyped a total number of 77 patients with MDS from Chinese Southern Han and 745 healthy controls for the

resultsWe found that neither the

conclusionOur results showed that HLA-Bw4 ligand and KIR3DL1-HLA-Bw4 combination could confer a protective effect against MDS in Chinese Southern Han.

Indexed as

GenotypeAdolescentAdultAgedAged, 80 and overAsian PeopleChinaFemaleHLA-B AntigensHumansMaleMiddle AgedMyelodysplastic SyndromesReceptors, KIR3DL1HLA-B AntigensHLA-Bw4 antigenKIR3DL1 protein, humanReceptors, KIR3DL1

Identifiers

PMID32420357
PMCPMC7210520
OpenAlexW3021109091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.