ArticleInternational journal of ophthalmology2020
Optical coherence tomography angiography of the peripapillary region and macula in normal, primary open angle glaucoma, pseudoexfoliation glaucoma and ocular hypertension eyes.
Article in International journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Corneal endothelial and retinal microvascular changes in pseudoexfoliation syndrome: insights from specular microscopy and OCT angiography.BMC ophthalmology · 2025Article
- Comparing structural and vascular parameters between advanced pseudoexfoliation glaucoma and primary open angle glaucoma using optical coherence tomography angiography.BMC ophthalmology · 2025Article
- The relationship of macular vessel density and foveal avascular zone with pulse wave velocity and central blood pressure in healthy adults: Persian cohort study.International journal of retina and vitreous · 2024Article
- The central retina vessel density and foveal avascular zone values of 792 healthy adults using optical coherence tomography angiography.Eye (London, England) · 2024Article
- SUPERFICIAL VESSEL DENSITY, RETINAL NERVE FIBER LAYER THICKNESS, AND VISUAL FIELD LOSS IN PRIMARY OPEN-ANGLE AND PSEUDOEXFOLIATIVE GLAUCOMA.Acta clinica Croatica · 2024Article
- Cardiac Surgery Patients Have Reduced Vascularity and Structural Defects of the Retina Similar to Persons with Open-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2024Article
- Repeatability, interocular correlation and agreement of optic nerve head vessel density in healthy eyes: a swept-source optical coherence tomographic angiography study.International journal of ophthalmology · 2024Article
- Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options.Turkish journal of ophthalmology · 2023Review
- Factors Associated with Vascular Changes at the Level of Retinal Ganglion Cell Axon versus Soma/Dendrite in Glaucoma Patients.Journal of clinical medicine · 2023Article
- Retinal thickness and fundus blood flow density changes in chest pain subjects with dyslipidemia.International journal of ophthalmology · 2023Article
- The Role of Vessel Density as Measured by Optical Coherence Tomography Angiography in the Evaluation of Pseudoexfoliative Glaucoma: A Review of the Literature.Ophthalmology and therapy · 2022Review
- Article
- Clinical Analysis of Macular Choroidal Thickness in Pseudoexfoliative Glaucoma and Primary Open-Angle Glaucoma.Journal of ophthalmology · 2021Article
- Magnitude of Diurnal Change in Retinal Vessel Density: Comparison Between Exfoliative Glaucoma and Primary Open-Angle Glaucoma.Beyoglu eye journal · 2021Article
- A comparison study of Optical Coherence Tomography Angiography Peripapillary Vessel Density in Early Glaucomatous and Normal Nigerian Eyes.Nigerian medical journal : journal of the Nigeria Medical AssociationReview
- Clinico-demographic Profile of Patients with Early Primary Open Angle Glaucoma at a Tertiary Private Eye Hospital in Lagos, Nigeria.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
- Optical Coherence Tomography Angiography Vessel Density in Healthy, Pseudoexfoliation Syndrome and Exfoliative Glaucoma: Diagnostic Accuracy and Relationship with Structural Parameters.Journal of current ophthalmologyArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate and compare the peripapillary and retinal vasculature changes in primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PXG), ocular hypertension (OHT) and normal eyes using optical coherence tomography angiography (OCTA).
methodsA total of 114 POAG, PXG and OHT eyes of 60 patients and 46 eyes of 23 healthy control participants with good quality OCTA images were included. The PXG, POAG, OHT, and control groups (aged 68.17±6.30y, 61.11±10.26y, 58.1±8.9y, and 56.9±4.6y, respectively) contained of 46, 36, 32, and 46 eyes, respectively. Measurements of vessel density (VD) in the peripapillary region and macula, average retinal inner thickness, and retinal nerve fiber layer thickness (RNFLT) were compared among groups. In order to test the accuracy of differentiation between eyes with and without glaucoma, the area was calculated under the receiver operating characteristic (ROC) curves.
resultsThe VD in glaucomatous eyes was significantly lower than the control group in all peripapillary sectors (44.35%±6.78%
conclusionOCTA can measure reduced peripapillary and macular VD in eyes with glaucoma and OHT, and these results are correlated to functional and structural glaucomatous alterations. Peripapillary and macular superficial plexus VD is lower in eyes with PXG than in eyes with POAG. Furthermore, the OHT eyes demonstrate impaired macular vasculature in both superficial and deep plexus.
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