Evidence map›Paper›PMID 32420091›Full record

ArticleCardiovascular diagnosis and therapy2020

Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice.

Yuchen He, Yanshuo Han, Jia Xing, Xiaoyue Zhai, Shiyue Wang, Shijie Xin, Jian Zhang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Structural and functional characterization of human kallistatin.Biochemistry and biophysics reports · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuchen HeDepartment of Vascular Surgery, The First Hospital of China Medical University, Shenyang 110001, China.
Yanshuo HanDepartment of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Jia XingDepartment of Histology and Embryology, China Medical University, Shenyang 110122, China.
Xiaoyue ZhaiDepartment of Histology and Embryology, China Medical University, Shenyang 110122, China.
Shiyue WangDepartment of Vascular Surgery, The First Hospital of China Medical University, Shenyang 110001, China.
Shijie XinDepartment of Vascular Surgery, The First Hospital of China Medical University, Shenyang 110001, China.
Jian ZhangDepartment of Vascular Surgery, The First Hospital of China Medical University, Shenyang 110001, China.
First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKallistatin (KS), encoded by

methodsWe examined KS (

resultsIn AAA tissue samples, KS was significantly increased compared with samples from the control group (P<0.001, P<0.001, respectively). Clinically, decreased

conclusionsThe present study demonstrates that aberrant changes in KS expression occur in AAA. KS plays an important anti-inflammatory role and showed important clinical correlations in AAA. Decreased KS (

Indexed as

Abdominal aortic aneurysm (AAA)inflammationserine proteinase inhibitors (SERPINs)

Identifiers

PMID32420091
PMCPMC7225437
OpenAlexW2999606570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.