Evidence map›Paper›PMID 32419926›Full record

ArticleF1000Research

Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target.

Veljko Veljkovic, Júlia Vergara-Alert, Joaquim Segalés, Slobodan Paessler

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in F1000Research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04382768 (Extended Compassionate Use Program), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04382768 naunknown statusnot on this map

Extended Compassionate Use Program (UCA) With Inhalational Ibuprofen in Patients With Acute Respiratory Pathology, Mediated by COVID-19.

TypeinterventionalSponsorQuímica Luar SRLRan2020 to 2021Enrolled40ConditionsCoronavirus Infection, Respiratory Disease, SARS (Disease)ArmsInhaled Hypertonic ibuprofen
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. SARS-CoV-2 PLChemistryOpen · 2024
    Article
  4. Article
  5. Zebrafish models of COVID-19.FEMS microbiology reviews · 2023
    Review
  6. AnJournal of biomolecular structure & dynamics · 2022
    Article
  7. mBio · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The SARS-CoV-2 outbreak from a one health perspective.One health (Amsterdam, Netherlands) · 2020
    Article
  17. Review
  18. Coronavirus Disease 2019-COVID-19.Clinical microbiology reviews · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Veljko VeljkovicBiomed Protection, Galveston, TX, 77550, USA.ORCID https://orcid.org/0000-0002-1980-0927
Júlia Vergara-AlertIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, Barcelona, 08193 Bellaterra, Spain.
Joaquim SegalésDepartament de Sanitat i Anatomia Animals, Universitat Autònoma de Barcelona (UAB), Barcelona, 08193 Bellaterra, Spain.
Slobodan PaesslerDepartment of Pathology, Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX, 77555, USA.
Universitat Autònoma de Barcelona · ESBiomed Protection (United States) · USThe University of Texas Medical Branch at Galveston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel coronavirus recently identified in Wuhan, China (SARS-CoV-2) has expanded the number of highly pathogenic coronaviruses affecting humans. The SARS-CoV-2 represents a potential epidemic or pandemic threat, which requires a quick response for preparedness against this infection. The present report uses the informational spectrum methodology to identify the possible origin and natural host of the new virus, as well as putative therapeutic and vaccine targets. The performed

Indexed as

COVID-19 VaccinesViral TropismAngiotensin-Converting Enzyme 2ChinaCOVID-19HumansReceptors, VirusSARS-CoV-2Spike Glycoprotein, CoronavirusACE2 protein, humanAngiotensin-Converting Enzyme 2COVID-19 VaccinesReceptors, VirusSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-22019-nCoVMERSSARSWuhan coronavirus

Identifiers

PMID32419926
PMCPMC7202090.4
OpenAlexW3001515529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.