ReviewAnnals of general psychiatry2020
The prevalence of depression among patients with tuberculosis: a systematic review and meta-analysis.
Review in Annals of general psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 8 of them syntheses that pooled it.
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Who cites it
77 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Adverse events in bedaquiline- and pretomanid-based regimens for drug-resistant tuberculosis from trial, implementation and pharmacovigilance studies.British journal of clinical pharmacology · 2026Pooled it
- Prevalence and Predictors of Anxiety among Tuberculosis Patients in India: A Systematic Review and Meta-Analysis.Journal of epidemiology and global health · 2026Pooled it
- Prevalence of depression in people with tuberculosis in East Africa: a systematic review and meta-analysis.African health sciences · 2023Pooled it
- Prevalence of Tuberculosis and Mental Disorders Comorbidity: A Systematic Review and Meta-analysis.Journal of immigrant and minority health · 2022Pooled it
- Satisfaction of tuberculosis patients to healthcare services at the global level: A systematic review.Health & social care in the community · 2022Pooled it
- Prevalence and risks of tuberculosis multimorbidity in low-income and middle-income countries: a meta-review.BMJ open · 2022Pooled it
- The relationship between mental health and risk of active tuberculosis: a systematic review.BMJ open · 2022Pooled it
- The Global Landscape of the Burden of Depressive Symptoms/Major Depression in Individuals Living With HIV/AIDs and Its Effect on Antiretroviral Medication Adherence: An Umbrella Review.Frontiers in psychiatry · 2022Pooled it
- Cognitive-behavioral therapy on psychological stress and quality of life in subjects with pulmonary tuberculosis: a community-based cluster randomized controlled trial.BMC public health · 2022Trial
- Qualitative study of patient experiences of mental distress during TB investigation and treatment in Zambia.BMC psychology · 2022Trial
- Article
- Longitudinal associations among insomnia, stigma, social support, and depressive symptoms in tuberculosis: evidence from RI-CLPM and LGCM.BMC public health · 2026Article
- Stigma and depression among patients with tuberculosis in Khyber Pakhtunkhwa Pakistan: a cross-sectional study.BMC public health · 2026Article
- Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches.Advances in respiratory medicine · 2026Article
- Psychosocial factors associated with depression and sleep quality in patients with tuberculosis: a multicenter cross-sectional study.Journal of thoracic disease · 2026Article
- Factors associated with depression among tuberculosis patients with HIV co-infection in rural community Thailand.BMC psychology · 2026Article
- High prevalence of persistent tuberculosis-related symptoms 6 months after treatment in pulmonary tuberculosis.BMJ open respiratory research · 2026Observational
- Post-tuberculosis Health: A Holistic Perspective on Multisystem Sequelae and Long-Term Wellbeing.Tuberculosis and respiratory diseases · 2026Article
- Suicide risk in people with tuberculosis in Republic of Korea: a nationwide cohort, 2012-2021.Infectious diseases of poverty · 2026Article
- Post-TB care in the UK: a national survey of existing practice.BMJ open respiratory research · 2026Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence has shown that the prevalence of depression is much higher among patients with tuberculosis (TB) and this, in turn, may adversely impact compliance with anti-TB medications. Therefore, this systematic review and meta-analysis aimed to quantitatively summarize epidemiologic evidence on the prevalence of depression among patients with TB and formulate a recommendation for future clinical practice as well as research.
methodsWe followed the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines to conduct this review. We searched PubMed, EMBASE, SCOPUS and Psych INFO to identify relevant studies that investigated the prevalence of depression among TB patients. We also supplemented our electronic search with manual searching to include all pertinent studies in the analysis. We used a Comprehensive Meta-Analysis software version 3.0 (CMA 3.0) to conduct a meta-analysis. We conducted a subgroup and sensitivity analysis and Cochran's
resultsWe identified a total of 25 studies that included 4903 participants across seven countries. In our analysis, the pooled estimated prevalence of depression among TB patients was found to be 45.19% (95% CI 38.04-52.55). The prevalence was higher in MDR-TB 52.34% (95% CI 38.09-66.22) than non-MDR-TB 43.47% (95% CI 35.88-51.37) patients. We also found that the pooled prevalence of depression was higher among females 51.54% (95% CI 40.34-62.60) when compared to males 45.25% (95% CI 35.19-55.71). The pooled prevalence of depression was 45.45% as measured by HRDS, and it was 55.62%, 45.52%, and 38.36% as measured by BDI, HADS and PHQ-9, respectively.
conclusionOur finding suggested that the pooled estimated prevalence of depression among tuberculosis patients was relatively high. Screening and management of depression among TB patients were warranted to alleviate suffering. Moreover, the integration of tuberculosis program with regular psychiatry services may substantially reduce the burden.
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