Evidence map›Paper›PMID 32419812›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Antidiarrheal Activity of Hydromethanolic Root Extract and Solvent Fractions of

Dessie Zayede, Tafere Mulaw, Wubayehu Kahaliw

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Phytochemical profiling and antidiarrheal activity of Sophora japonica L. fruit extract.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Article
  2. Sustainable Utilization of Agricultural By-Products:Journal of pharmacopuncture · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Journal of tropical medicine · 2024
    Article
  8. Article
  9. UHPLC-MS profiles and antidiarrheal activity ofFrontiers in pharmacology · 2023
    Article
  10. Review
  11. Evaluation ofMetabolism open · 2022
    Article
  12. Article
  13. Article
  14. Evaluation of the Antiulcer Activity of Methanolic Extract and Solvent Fractions of the Leaves ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  15. Article
  16. Article
  17. Antidiarrheal Effect of 80% Methanol Extract and Fractions ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  18. Evaluation ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  19. Methanolic Crude Extract ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dessie ZayedeUniversity of Gondar, P. O. Box: 196, Gondar, Ethiopia.
Tafere MulawDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, P. O. Box: 196, Gondar, Ethiopia.
Wubayehu KahaliwDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, P. O. Box: 196, Gondar, Ethiopia.ORCID https://orcid.org/0000-0002-4197-4413
University of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiarrheal diseases are associated with an estimated 1.3 million deaths annually, with most occurring in resource-limited countries; up to 25% of deaths in young children living in Africa and southeast Asia are attributable to acute gastroenteritis. Due to limitations associated with various treatments available, the need for developing newer drugs is imperative.

objectiveThis study was aimed to evaluate the antidiarrheal activity of root extract and fractions of

methodsAfter plant extraction and subsequent fractionation of the crude extract, the antidiarrheal activity was screened in castor oil induced diarrhea, castor oil induced enteropooling, and gastrointestinal motility test models accordingly.

resultThe root extract of

conclusionThe results obtained showed that the findings provide scientific support for the folkloric repute of

Identifiers

PMID32419812
PMCPMC7201494
OpenAlexW2999283991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.