ReviewJournal of the American Heart Association2020
Atrioventricular Valve Regurgitation in Single Ventricle Heart Disease: A Common Problem Associated With Progressive Deterioration and Mortality.
Review in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Extracorporeal Membrane Oxygenation in the Interstage Period After Norwood and Related Stage I Palliations in Infants With Single Ventricle: A Systematic Review of Incidence, Risk Factors, and Outcomes.Journal of the American Heart Association · 2026Pooled it
- Atrial Isomerism Adversely Impaired both Early and Late Outcomes in Fontan Circulation.Pediatric cardiology · 2026Article
- Structural Heart Interventions in Women with Congenital Heart Disease.Current cardiology reports · 2026Review
- Measuring atrioventricular valve regurgitation in Fontan patients using cardiovascular magnetic resonance imaging and the association with clinical outcomes: A FORCE Study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026Article
- Functionally Single-Ventricle Complications After Fontan Palliation-A Narrative Review.Journal of clinical medicine · 2026Review
- Heart and combined heart-liver transplantation in Asian patients with Fontan circulatory failure: a single-center experience.Journal of cardiothoracic surgery · 2026Article
- Transcatheter closure of the right atrioventricular valve in a double-inlet left ventricle patient following fontan operation.Turk gogus kalp damar cerrahisi dergisi · 2026Article
- Mid-term outcomes of valvuloplasty versus mechanical valve replacement for the common atrioventricular valve in single-ventricle pediatric patients.World journal of pediatric surgery · 2026Article
- Three-Dimensional Echocardiography in Congenital Heart Disease: Comparison with Pathologic Specimens-A Case Series.CASE (Philadelphia, Pa.) · 2025Article
- A noninvasive method for determining elastic parameters of valve tissue using physics-informed neural networks.Acta biomaterialia · 2025Article
- Assessment of hemodynamic disturbances and impaired ventricular filling in asymptomatic fontan patients: A 4D flow CMR study.European journal of radiology open · 2025Article
- Are We Getting Better?: Ongoing Challenges of Atrioventricular Valve Repair in Children With Single Ventricle Physiology.Journal of the American Heart Association · 2025Article
- Article
- Optimal timing of bridging annuloplasty and patch augmentation for heterotaxy syndrome associated with functional single ventricles.General thoracic and cardiovascular surgery · 2025Article
- Ventricular assist device implantation in children with a mechanical valve: An ACTION registry analysis.JHLT open · 2025Article
- High-Performing Fontan Patients: A Fontan Outcome Registry by Cardiac Magnetic Resonance Imaging Study.JACC. Advances · 2024Article
- Impact of Pulmonary Artery Banding in Patients with Congenital Heart Disease and Pulmonary Hypertension.Reviews in cardiovascular medicine · 2024Article
- Impact of heart failure on reoperation in adult congenital heart disease: An innovative machine learning model.The Journal of thoracic and cardiovascular surgery · 2024Article
- Contemporary Management of the Failing Fontan.Journal of clinical medicine · 2024Review
- Mid-term outcomes of atrioventricular valve repair in functional single ventricle patients.Frontiers in cardiovascular medicine · 2024Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Fontan procedure has provided patients with single ventricle physiology extended survival into adulthood and in many cases has improved their quality of life. Atrioventricular valve regurgitation (AVVR) is common in single ventricle patients and is associated with increased risk of mortality. AVVR is more common in patients with a systemic tricuspid or common atrioventricular valve but is generally progressive irrespective of underlying valve morphology. AVVR can be attributable to diverse structural and functional abnormalities at multiple levels of the valvar apparatus, as well as ventricular dysfunction and dilation. Multiple imaging modalities including recent advances in 3-dimensional echocardiography and cross-sectional imaging have been used to further understand AVVR. Surgery to address AVVR must be tailored to the underlying mechanism and the timing of surgical repair should be chosen carefully. In this review, we discuss the etiologies, treatment options, surgical timing, and outcomes of valve repair or replacement for AVVR in patients with single ventricle congenital heart disease, with a focus on those with a Fontan circulation as AVVR is associated with increased risk for Fontan failure and mortality. In-depth understanding of the current literature will help guide clinicians in their approach and management of AVVR in this population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.