SynthesisClinics and research in hepatology and gastroenterology2020
The liver injury and gastrointestinal symptoms in patients with Coronavirus Disease 19: A systematic review and meta-analysis.
Synthesis in Clinics and research in hepatology and gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04854941 (Efficacy of Probiotics), which is not on this map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Probiotics (Lactobacillus Rhamnosus, Bifidobacterium Bifidum, Bifidobacterium Longum Subsp. Infantis and Bifidobacterium Longum) in the Treatment of Hospitalised Patients With Novel Coronavirus Infection
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Are gastrointestinal symptoms associated with higher risk of Mortality in COVID-19 patients? A systematic review and meta-analysis.BMC gastroenterology · 2022Pooled it
- Effect of COVID-19 on liver abnormalities: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Is liver involvement overestimated in COVID-19 patients? A meta-analysis.International journal of medical sciences · 2021Pooled it
- Systematic review with meta-analysis: liver manifestations and outcomes in COVID-19.Alimentary pharmacology & therapeutics · 2020Pooled it
- Predictors of mortality in hospitalized African American COVID-19 patients with cancer.Translational cancer research · 2024Article
- Artificial intelligence based health indicator extraction and disease symptoms identification using medical hypothesis models.Cluster computing · 2022Article
- Gastrointestinal Involvement in SARS-CoV-2 Infection.Viruses · 2022Review
- Global research production pertaining to gastrointestinal involvement in COVID-19: A bibliometric and visualised study.World journal of gastrointestinal surgery · 2022Article
- Scoping review of COVID-19-related systematic reviews and meta-analyses: can we really have confidence in their results?Postgraduate medical journal · 2022Article
- Review
- COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms.Clinics and research in hepatology and gastroenterology · 2022Review
- Digestive System Involvement During Coronavirus Disease 2019; the Newest Clinical Features and Potential Mechanisms : Digestive System Involvements and COVID-19.Galen medical journal · 2022Review
- Clinical presentation of COVID-19 in patients with inflammatory bowel disease: a systematic review and meta-analysis.Intestinal research · 2022Article
- Dynamic Changes of Liver Function Indexes in Patients with Different Clinical Types of COVID-19.International journal of general medicine · 2022Article
- Gastrointestinal manifestations in patients with coronavirus disease-2019 (COVID-19): Impact on clinical outcomes.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Article
- Impact of COVID-19 on digestive system: prevalence, clinical characteristics, outcome, and relation to the severity of COVID-19.The Egyptian journal of internal medicine · 2022Article
- Gastrointestinal manifestations of SARS-CoV-2 infection in an Italian population of hospitalized patients.Therapeutic advances in gastroenterology · 2022Article
- Hepatic and gastrointestinal disturbances in Egyptian patients infected with coronavirus disease 2019: A multicentre cohort study.World journal of gastroenterology · 2021Article
- Liver injury in COVID-19: Known and unknown.World journal of clinical cases · 2021Review
- Angiotensin-converting enzyme 2 receptors, chronic liver diseases, common medications, and clinical outcomes in coronavirus disease 2019 patients.World journal of virology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Backgrounds: Since December 2019, novel coronavirus (SARS-CoV-2)-infected pneumonia (COVID-19) occurred in Wuhan, and rapidly spread throughout China. Our study aimed to evaluate the association of liver injury and gastrointestinal symptoms (GIS) with the progression of COVID-19. Methods: A comprehensive search was performed on the PubMed to identify eligible studies that summarized the liver injury and GIS in COVID-19. Results: A total of 21 studies with 3024 patients were included. Up to 53% patients had liver dysfunctions and the degree of liver damage was associated the severity of the disease. The prevalence of diarrhoea, nausea/vomiting or abdominal pain in patients with COVID-19 were 9.1%, 5.2% and 3.5%, respectively. No significant was found in the prevalence of diarrhoea (OR, 1.24; 95%CI, 0.90 to 1.72; Conclusions: The incidences of GIS in patients with COVID-19 is relatively low and are not associated with the COVID-19 progression. Gastroenterologists should pay more attention to the liver injury induced by SARS-CoV-2 during the course of infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.