Evidence map›Paper›PMID 32418346›Full record

ArticleJournal of veterinary internal medicine2020

Association between anesthesia duration and outcome in dogs with surgically treated acute severe spinal cord injury caused by thoracolumbar intervertebral disk herniation.

Joe Fenn, Hongyu Ru, Nick D Jeffery, Sarah Moore, Andrea Tipold, Franz J Soebbeler, Adriano Wang-Leandro, Christopher L Mariani, Peter J Early, Karen R Muñana and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

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  4. Epidemiology of CanineAnimals : an open access journal from MDPI · 2024
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  13. Influence of Spinal Shock on the Neurorehabilitation of ANNPE Dogs.Animals : an open access journal from MDPI · 2022
    Article
  14. Outcome of thoracolumbar surgical feline intervertebral disc disease.Journal of feline medicine and surgery · 2022
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Joe FennDepartment of Clinical Science and Services, Royal Veterinary College, Hertfordshire, United Kingdom.ORCID https://orcid.org/0000-0001-7851-670X
Hongyu RuDepartment of Statistics, North Carolina State University, Raleigh, North Carolina, USA.
Nick D JefferyThe Canine Spinal Cord Injury Consortium (CANSORT-SCI).
Sarah MooreThe Canine Spinal Cord Injury Consortium (CANSORT-SCI).ORCID https://orcid.org/0000-0002-4311-6199
Andrea TipoldThe Canine Spinal Cord Injury Consortium (CANSORT-SCI).
Franz J SoebbelerDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany.
Adriano Wang-LeandroDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany.ORCID https://orcid.org/0000-0003-2991-5696
Christopher L MarianiDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0003-3228-6536
Peter J EarlyDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0003-3399-8500
Karen R MuñanaDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0001-9592-6276
Natasha J OlbyThe Canine Spinal Cord Injury Consortium (CANSORT-SCI).ORCID https://orcid.org/0000-0003-1349-3484
North Carolina State University · USUniversity of Veterinary Medicine Hannover, Foundation · DERoyal Veterinary College · GBTexas College · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetrospective research recently identified a possible relationship between duration of surgery and outcome in severely affected dogs treated surgically for acute thoracolumbar intervertebral disk herniation (TL-IVDH). HYPOTHESIS: That increased duration of surgery is associated with poorer outcome in dogs with absent pain perception treated surgically for TL-IVDH. ANIMALS: Two hundred ninety-seven paraplegic dogs with absent pain perception surgically treated for acute TL-IVDH.

methodsRetrospective cohort study. Medical records of 5 institutions were reviewed. Inclusion criteria were paraplegia with absence of pain perception, surgical treatment of TL-IVDH, and 1-year postoperative outcome (ambulatory: yes or no). Canine data, outcome, and surgery and total anesthesia duration were retrieved.

resultsIn this study, 183/297 (61.6%) dogs were ambulatory within 1 year, 114 (38.4%) dogs failed to recover, including 74 dogs (24.9%) euthanized because of progressive myelomalacia. Median anesthesia duration in dogs that regained ambulation within 1 year of surgery (4.0 hours, interquartile range [IQR] 3.2-5.1) was significantly shorter than those that did not (4.5 hours, IQR 3.7-5.6, P = .01). Multivariable logistic regression demonstrated a significant negative association between both duration of surgery and total anesthesia time and ambulation at 1 year when controlling for body weight and number of disk spaces operated on. CONCLUSIONS AND CLINICAL IMPORTANCE: Findings support a negative association between increased duration of anesthesia and outcome in this group of dogs. However, the retrospective nature of the data does not imply a causal relationship.

Indexed as

Operative TimeAnesthesiaAnimalsCohort StudiesDog DiseasesDogsFemaleIntervertebral Disc DegenerationIntervertebral Disc DisplacementLaminectomyMalePainParaplegiaRetrospective StudiesSpinal Cord InjuriesTreatment Outcomecanineextrusionhemilaminectomyprognosissurgery

Identifiers

PMID32418346
PMCPMC7379036
OpenAlexW3024799182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.