Evidence map›Paper›PMID 32418337›Full record

ReviewMedical physics2020

Machine learning techniques for biomedical image segmentation: An overview of technical aspects and introduction to state-of-art applications.

Hyunseok Seo, Masoud Badiei Khuzani, Varun Vasudevan, Charles Huang, Hongyi Ren, Ruoxiu Xiao, Xiao Jia, Lei Xing

Abstract readReview
In one paragraph

Review in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Artificial intelligence for segmentation and classification in lumbar spinal stenosis: an overview of current methods.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. A two-stage deep learning system for cervical spine fracture diagnosis: integrating 3D segmentation and 2.5D classification on CT images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Quality Assurance Strategies for Brain State Characterization by MEMRI.bioRxiv : the preprint server for biology · 2026
    Article
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  10. Deep Learning Tools for Single Quantum Dot Tracking.Methods in molecular biology (Clifton, N.J.) · 2026
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  19. Article
  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyunseok SeoMedical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
Masoud Badiei KhuzaniMedical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
Varun VasudevanInstitute for Computational and Mathematical Engineering, School of Engineering, Stanford University, Stanford, CA, 94305-4042, USA.
Charles HuangDepartment of Bioengineering, School of Engineering and Medicine, Stanford University, Stanford, CA, 94305-4245, USA.
Hongyi RenMedical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
Ruoxiu XiaoMedical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
Xiao JiaMedical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.
Lei XingMedical Physics Division in the Department of Radiation Oncology, School of Medicine, Stanford University, Stanford, CA, 94305-5847, USA.

Funding

STANFORD CANCER IMAGING TRAINING (SCIT) PROGRAMT32CA009695 · NCI · STANFORD UNIVERSITY · PI BRUCE L DANIEL, Jeremy Dahl · 1993 to 2026
$7.7M
Dual Modality X-ray Luminescence CT for in vivo Cancer ImagingR01CA227713 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2019 to 2023
$2.9M
Radioluminescence dosimetry solution for precision radiation therapyR01CA223667 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2018 to 2022
$2.4M
DASSIM-RT and Compressed Sensing-Based Inverse PlanningR01CA176553 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2014 to 2018
$2.4M
GoogleHuiyihuiying Medical CoNCI NIH HHS R01 CA176553NCI NIH HHS R01 CA223667NCI NIH HHS R01 CA227713NCI NIH HHS T32 CA009695NIH HHS 1R01 CA176553Varian Medical Systems
6 · The paper itself

Abstract

In recent years, significant progress has been made in developing more accurate and efficient machine learning algorithms for segmentation of medical and natural images. In this review article, we highlight the imperative role of machine learning algorithms in enabling efficient and accurate segmentation in the field of medical imaging. We specifically focus on several key studies pertaining to the application of machine learning methods to biomedical image segmentation. We review classical machine learning algorithms such as Markov random fields, k-means clustering, random forest, etc. Although such classical learning models are often less accurate compared to the deep-learning techniques, they are often more sample efficient and have a less complex structure. We also review different deep-learning architectures, such as the artificial neural networks (ANNs), the convolutional neural networks (CNNs), and the recurrent neural networks (RNNs), and present the segmentation results attained by those learning models that were published in the past 3 yr. We highlight the successes and limitations of each machine learning paradigm. In addition, we discuss several challenges related to the training of different machine learning models, and we present some heuristics to address those challenges.

Indexed as

Diagnostic ImagingMachine LearningHumansImage Processing, Computer-Assisteddeep learningmachine learningmedical Imageoverviewsegmentation

Identifiers

PMID32418337
PMCPMC7338207

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.