Evidence map›Paper›PMID 32418273›Full record

ArticleJournal of biomedical materials research. Part A2021

3D bioprinting of oligo(poly[ethylene glycol] fumarate) for bone and nerve tissue engineering.

Xifeng Liu, Bipin Gaihre, Matthew N George, A Lee Miller, Haocheng Xu, Brian E Waletzki, Lichun Lu

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Bioprinting of gelatin-based materials for orthopedic application.Frontiers in bioengineering and biotechnology · 2024
    Review
  5. Effective and new technologies in kidney tissue engineering.Frontiers in bioengineering and biotechnology · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Emerging Technologies in Multi-Material Bioprinting.Advanced materials (Deerfield Beach, Fla.) · 2021
    Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xifeng LiuDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-2684-6309
Bipin GaihreDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Matthew N GeorgeDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
A Lee MillerDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Haocheng XuDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Brian E WaletzkiDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Lichun LuDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Metastatic Spine Tumors: Minimally Invasive Fracture Risk Analysis and Treatment - MasterR01AR056212 · NIAMS · MAYO CLINIC ROCHESTER · PI Benjamin D Elder, Lichun Lu · 2008 to 2026
$6.2M
NIAMS NIH HHS R01 AR056212
6 · The paper itself

Abstract

3D bioprinting is a promising new tissue restoration technique that enables the precise deposition of cells and growth factors in order to more closely mimic the structure and function of native organs. In this study, we report the development of a new bioink using oligo(poly[ethylene glycol] fumarate) (OPF), a photo-crosslinkable, and biodegradable polymer, for 3D bioprinting. In addition to OPF, a small portion of gelatin was also incorporated into the bioink to make it bio-printable. After immersion in the cell medium, gelatin was eluted away to create a bioprinted scaffold of pure OPF. Excellent cell viability, spreading, and long-term proliferation of encapsulated cells was observed using both bone and nerve cells as examples. These results demonstrate that OPF bioink has great potential in future 3D bioprinting applications that aim to replicate complex, layered tissues, and/or organs.

Indexed as

Printing, Three-Dimensional3T3 CellsAnimalsBioprintingBone and BonesBone RegenerationCell ProliferationCell SurvivalCross-Linking ReagentsFumaratesGelatinHydrogelsMiceNerve RegenerationNerve TissueNeuronsCross-Linking ReagentsFumaratesGelatinHydrogelspoly(ethylene glycol fumarate)Polyethylene Glycols3D bioprintingbioinkhydrogeloligo(poly[ethylene glycol] fumarate)tissue engineering

Identifiers

PMID32418273
PMCPMC8942303
OpenAlexW3025259070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.