Evidence map›Paper›PMID 32418206›Full record

ArticleJournal of neurochemistry2021

Fluorescence lifetime imaging reveals regulation of presynaptic Ca

Olga Tyurikova, Kaiyu Zheng, Elizabeth Nicholson, Yulia Timofeeva, Alexey Semyanov, Kirill E Volynski, Dmitri A Rusakov

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Olga TyurikovaQueen Square Institute of Neurology, University College London, London, UK.
Kaiyu ZhengQueen Square Institute of Neurology, University College London, London, UK.
Elizabeth NicholsonQueen Square Institute of Neurology, University College London, London, UK.
Yulia TimofeevaQueen Square Institute of Neurology, University College London, London, UK.
Alexey SemyanovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Kirill E VolynskiQueen Square Institute of Neurology, University College London, London, UK.ORCID 0000-0001-8208-1905
Dmitri A RusakovQueen Square Institute of Neurology, University College London, London, UK.ORCID 0000-0001-9539-9947
National Hospital for Neurology and Neurosurgery · GBInstitute of Bioorganic Chemistry · RUSechenov University · RUUniversity of Warwick · GB

Funding

Wellcome Trust 104033/Z/14/ZWellcome Trust 212251/Z/18/ZWellcome Trust 212251_Z_18_ZWellcome Trust 323113Wellcome Trust 857562
6 · The paper itself

Abstract

Brain function relies on vesicular release of neurotransmitters at chemical synapses. The release probability depends on action potential-evoked presynaptic Ca

Indexed as

AnimalsCalciumCerebral CortexGlutamic AcidMiceMice, Inbred C57BLNeuronsNeurotransmitter AgentsOptical ImagingPresynaptic TerminalsReceptors, Metabotropic GlutamateSynapsesSynaptic TransmissionCalciumGlutamic AcidNeurotransmitter AgentsReceptors, Metabotropic Glutamateaxonscalcium imagingneurotransmitter releasepresynaptic mechanismssynapsesynaptic plasticity

Identifiers

PMID32418206
PMCPMC8436763
OpenAlexW3025358356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.