Evidence map›Paper›PMID 32418202›Full record

ArticleThe Journal of pathology2020

Effect of VEGFC on lymph flow and inflammation-induced alveolar bone loss.

Hua Wang, Yuyi Chen, Wenlei Li, Lian Sun, Hongyu Chen, Qiudong Yang, Hang Zhang, Weibing Zhang, Hua Yuan, Hengwei Zhang and 2 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Hua WangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Yuyi ChenJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Wenlei LiJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Lian SunJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Hongyu ChenJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Qiudong YangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Hang ZhangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Weibing ZhangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Hua YuanJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.
Hengwei ZhangDepartment of Pathology and Laboratory Medicine and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.
Lianping XingDepartment of Pathology and Laboratory Medicine and Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.
Wen SunJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.ORCID 0000-0002-8111-8865
Stomatology Hospital · CNUniversity of Rochester Medical Center · US

Funding

Synovial lymphatics and osteoarthritis in agingR01AG059775 · NIA · UNIVERSITY OF ROCHESTER · PI XING, LIANPING · 2020 to 2024
$1.9M
NIA NIH HHS R01 AG059775
6 · The paper itself

Abstract

The lymphatic system plays a crucial role in the maintenance of tissue fluid homeostasis and the immunological response to inflammation. The effects of lymphatic drainage dysfunction on periodontitis have not been well studied. Here we show that lymphatic vessel endothelial receptor 1 (LYVE1)

Indexed as

Genetic TherapyAlveolar Bone LossAlveolar ProcessAnimalsCase-Control StudiesChronic PeriodontitisDisease Models, AnimalHumansLymphLymphatic VesselsMaleMaxillaMice, Inbred C57BLMice, TransgenicOsteoclastsTumor Necrosis Factor-alphaTNF protein, humanTumor Necrosis Factor-alphaVascular Endothelial Growth Factor CVEGFC protein, humanalveolar bone losslymphatic drainageperiodontitisTNF-Tg miceVEGFC

Identifiers

PMID32418202
PMCPMC10587832
OpenAlexW3026024135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.