Trial reportMedical principles and practice : international journal of the Kuwait University, Health Science Centre2021
Two-Year Survival of High-Viscosity Glass Ionomer in Children with Molar Incisor Hypomineralization.
Trial report in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Restorative interventions and management of primary and permanent molars affected by molar incisor hypo-mineralization: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Desensitization treatment in MIH-affected teeth: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- An update of treatment modalities in children and adolescents with teeth affected by molar incisor hypomineralisation (MIH): a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Pooled it
- Clinical performance of glass hybrid and short fiber-reinforced composite restorations in MIH-affected molars: A 60-month split-mouth randomized controlled trial.Clinical oral investigations · 2026Trial
- Zirconia-reinforced glass ionomer restorations in molar incisor hypomineralization: a randomized controlled clinical trial.Clinical oral investigations · 2025Trial
- Short-Term Changes in Occlusal Force Distribution and Masticatory Muscle Activity After Restorative Treatment in Children with Molar-Incisor Hypomineralization: An Exploratory Pilot Study.Children (Basel, Switzerland) · 2026Article
- Long-term evaluation of the success rate of different treatment modalities on MIH-affected teeth.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Article
- Key concepts for clinical management of Molar Incisor Hypomineralization.Brazilian oral research · 2026Review
- Bonding to Molar-Incisor Hypomineralization Affected Teeth: A Scoping Review of Adhesive Strategies, In Vitro Performance, and Clinical Outcomes.Frontiers in dentistry · 2026Review
- Therapeutic Alternatives in a Pediatric Patient With Molar Incisor Hypomineralization: A Clinical Case Report.Cureus · 2025Article
- Six-year survival and clinical performance of glass hybrid restorations following selective caries removal in teeth with molar incisor hypomineralization: a prospective cohort study.Clinical oral investigations · 2025Article
- Review
- Effects of Finishing on Surface Roughness of Four Different Glass-Ionomer Cements and One Alkasite: In Vitro Investigation over Time Using Aging Simulation.Journal of functional biomaterials · 2024Article
- 1-year Results of Molar Incisor Hypomineralization-affected Cases Treated with Silver Modified Atraumatic Restorative Treatment: A Retrospective Study.International journal of clinical pediatric dentistry · 2024Article
- Cost-effectiveness of restorative treatments for permanent molars with severe molar incisor hypomineralization: perspectives for the Brazilian public health system.Clinical oral investigations · 2024Article
- Treatment Alternative of Molar Incisor Hypomineralisation for Young Permanent Teeth: A Scoping Review.Clinical, cosmetic and investigational dentistry · 2024Article
- Article
- Contemporary Understanding of the Etiology and Management of Molar Incisor Hypomineralization: A Literature Review.Dentistry journal · 2023Review
- Follow-up of first permanent molar restorative treatment with and without Molar Hypomineralization.Acta odontologica latinoamericana : AOL · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe assessed the clinical survival of a high-viscosity glass ionomer (HVGI) at the 2-year follow-up to restore molar incisors severely affected by hypomineralization after selective carious tissue removal (SCR). The null hypothesis tested was that there are no differences in the overall survival times in the categories of the variables of interest.
methodsA total of 134 fully erupted first molar incisors with hypomineralization, cavitated and with moderate-to-deep carious lesions without hypersensitivity or pain (MIH treatment need index 2a-c), were included in the study. HVGI (Equia Forte®; GC, Tokyo, Japan) restorations were applied after SCR to soft carious dentin. The follow-up lasted 2 years. The end point was defined as the absence of endodontic and restorative complications. Two-year, and 18-, 12-, and 6-month survival probabilities and standard errors were calculated using the Kaplan-Meier method. Survival probabilities according to patient gender, jaw, and lesion severity groups were compared using the log-rank test. Restorations were evaluated using the modified US Public Health Service criteria.
resultsHVGI restorations showed cumulative survival probabilities of 95.5% at 6 months, 94% at 12 months, 87.5% at 18 months, and 87.5% at 24 months. Survival probabilities according to patient gender, jaw, and lesion severity groups were not statistically significantly different (p > 0.05). Therefore, the null hypothesis was accepted.
conclusionFollowing SCR, HVGI restoration provided moderate survival probabilities, suggesting that the SCR technique is effective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.